Evidence map›Paper›PMID 36051167›Full record

ArticleEuropean journal of case reports in internal medicine2022

Atypical Gradenigo Syndrome in an Elderly Man Resolved with Mastoidectomy and Petrous Apicectomy.

Azizullah Beran, Nameer Aladamat, Mustafa Alchalabi, Mohammed Mhanna, Omar Srour, Yasmin Khader, Ammar Kayyali

Open access · greenAbstract read
In one paragraph

Article in European journal of case reports in internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. [Inflammatory diseases of the petrous bone].Radiologie (Heidelberg, Germany) · 2025
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Azizullah BeranDepartment of Internal Medicine, University of Toledo, Toledo, OH, USA.
Nameer AladamatDepartment of Neurology, University of Toledo, Toledo, OH, USA.
Mustafa AlchalabiDepartment of Neurology, University of Toledo, Toledo, OH, USA.
Mohammed MhannaDepartment of Internal Medicine, University of Toledo, Toledo, OH, USA.
Omar SrourDepartment of Internal Medicine, University of Toledo, Toledo, OH, USA.
Yasmin KhaderDepartment of Internal Medicine, University of Toledo, Toledo, OH, USA.
Ammar KayyaliDepartment of Internal Medicine, University of Toledo, Toledo, OH, USA.
University of Toledo · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gradenigo syndrome (GS) was described primarily in the paediatric population, especially in the pre-antibiotic era. GS is rarely reported in the elderly population, especially in the post-antibiotic era. We present the rare case of a 67-year-old man who presented with an incomplete triad of symptoms (without abducens nerve palsy) of GS that failed medical therapy and was successfully treated with surgical intervention (mastoidectomy and petrous apicectomy). Physicians should be familiar with atypical presenting symptoms of GS as it can lead to life-threatening complications, especially in the elderly. GS cases resistant to medical therapy may require prompt appropriate imaging studies and surgical intervention. LEARNING POINTS: Gradenigo syndrome may present with an incomplete triad (without abducens nerve palsy), especially in the post-antibiotic era.Gradenigo syndrome can rarely affect immunocompromised elderly patients.Gradenigo syndrome cases resistant to medical therapy may require prompt appropriate imaging studies and surgical intervention (mastoidectomy and petrous apicectomy).

Indexed as

abducens nerve palsyelderlyGradenigo syndrome

Identifiers

PMID36051167
PMCPMC9426965
OpenAlexW4294354451

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.