Evidence map›Paper›PMID 36051055›Full record

ArticleEJHaem2022

An integrated prognostic model for diffuse large B-cell lymphoma treated with immunochemotherapy.

Marta Rodríguez, Ruth Alonso-Alonso, Ismael Fernández-Miranda, Rufino Mondéjar, Laura Cereceda, Álvaro Tráscasa, Anabel Antonio-Da Conceiçao, Jennifer Borregón, Lucía Gato, Laura Tomás-Roca and 25 more

Abstract read
In one paragraph

Article in EJHaem, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Marta RodríguezPathology Department IIS Hospital Universitario Fundación Jiménez Díaz Madrid Spain.ORCID https://orcid.org/0000-0001-8543-6767
Ruth Alonso-AlonsoPathology Department IIS Hospital Universitario Fundación Jiménez Díaz Madrid Spain.
Ismael Fernández-MirandaLymphoma Research Group IIS Puerta de Hierro-Segovia de Arana (IDIPHISA) Madrid Spain.
Rufino MondéjarCenter for Biomedical Network Research on Cancer (CIBERONC) ISCIII Madrid Spain.
Laura CerecedaPathology Department IIS Hospital Universitario Fundación Jiménez Díaz Madrid Spain.
Álvaro TráscasaPathology Department IIS Hospital Universitario Fundación Jiménez Díaz Madrid Spain.
Anabel Antonio-Da ConceiçaoPathology Department IIS Hospital Universitario Fundación Jiménez Díaz Madrid Spain.
Jennifer BorregónPathology Department IIS Hospital Universitario Fundación Jiménez Díaz Madrid Spain.
Lucía GatoPathology Department IIS Hospital Universitario Fundación Jiménez Díaz Madrid Spain.
Laura Tomás-RocaPathology Department IIS Hospital Universitario Fundación Jiménez Díaz Madrid Spain.
Carmen BárcenaPathology Department Hospital Universitario Doce de Octubre Madrid Spain.
Begoña IglesiasPathology Department Hospital Álvaro Cunqueiro Vigo Spain.
Fina ClimentPathology Department Hospital Universitari de Bellvitge L'Hospitalet de Llobregat Barcelona Spain.
Eva González-BarcaHaematology Department Institut Català d'Oncologia Hospital Duran i Reynals L'Hospitalet de Llobregat Barcelona Spain.
Francisca Inmaculada CamachoPathology Department Hospital Universitario de Getafe Madrid Spain.
Émpar MayordomoPathology Department Hospital Universitario y Politécnico La Fe Valencia Spain.
Gabriel OlmedillaPathology Department Hospital Universitario La Paz Madrid Spain.
Pilar Gómez-PrietoHaematology Department Hospital Universitario La Paz Madrid Spain.
Yolanda CastroPathology Department Hospital Universitario Príncipe de Asturias Madrid Spain.
Juana Serrano-LópezExperimental Hematology Laboratory IIS Hospital Universitario Fundación Jiménez Díaz Madrid Spain.
Joaquín Sánchez-GarcíaHaematology Department Hospital Universitario Reina Sofia Maimonides Biomedical Research Institute IMIBIC University of Córdoba Córdoba Spain.
Santiago Montes-MorenoCenter for Biomedical Network Research on Cancer (CIBERONC) ISCIII Madrid Spain.
Mónica García-CosíoCenter for Biomedical Network Research on Cancer (CIBERONC) ISCIII Madrid Spain.
Paloma Martín-AcostaCenter for Biomedical Network Research on Cancer (CIBERONC) ISCIII Madrid Spain.
Juan F GarcíaCenter for Biomedical Network Research on Cancer (CIBERONC) ISCIII Madrid Spain.
María PlanellesPathology Department Hospital General Universitario de Alicante Alicante Spain.
Cristina QueroClinical Oncology Department Hospital General Universitario Virgen de la Victoria Complejo Hospital Costa del Sol Marbella (Málaga) Spain.
Mariano ProvencioClinical Oncology Department IIS Puerta de Hierro-Segovia de Arana (IDIPHISA) Madrid Spain.
Ignacio Mahíllo-FernándezDepartment of Epidemiology IIS Hospital Universitario Fundación Jiménez Díaz Madrid Spain.ORCID https://orcid.org/0000-0003-0558-6541
Socorro M Rodríguez-PinillaPathology Department IIS Hospital Universitario Fundación Jiménez Díaz Madrid Spain.
Enrico DerenziniDivisions of Haemato-Oncology and Haematopathology IEO European Institute of Oncology IRCCS Milan Italy.
Stefano PileriDivisions of Haemato-Oncology and Haematopathology IEO European Institute of Oncology IRCCS Milan Italy.
Margarita Sánchez-BeatoCenter for Biomedical Network Research on Cancer (CIBERONC) ISCIII Madrid Spain.ORCID https://orcid.org/0000-0002-0058-7599
Raúl CórdobaCenter for Biomedical Network Research on Cancer (CIBERONC) ISCIII Madrid Spain.
Miguel A PirisPathology Department IIS Hospital Universitario Fundación Jiménez Díaz Madrid Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse large B-cell lymphoma (DLBCL), the most frequent non-Hodgkin's lymphoma subtype, is characterized by strong biological, morphological, and clinical heterogeneity, but patients are treated with immunochemotherapy in a relatively homogeneous way. Here, we have used a customized NanoString platform to analyze a series of 197 homogeneously treated DLBCL cases. The platform includes the most relevant genes or signatures known to be useful for predicting response to R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone) in DLBCL cases. We generated a risk score that combines the International Prognostic Index with cell of origin and double expression of

Indexed as

diffuse large B‐cell lymphomaDLBCLgene expressionimmunochemotherapyprognosis

Identifiers

PMID36051055
PMCPMC9422037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.