Evidence map›Paper›PMID 36051012›Full record

ArticleEJHaem2022

Second malignant neoplasms after treatment of 1487 children and adolescents with acute lymphoblastic leukemia-A population-based analysis of the Austrian ALL-BFM Study Group.

Fiona Poyer, Karin Dieckmann, Michael Dworzak, Melanie Tamesberger, Oskar Haas, Neil Jones, Karin Nebral, Stefan Köhrer, Reinhard Moser, Gabriele Kropshofer and 6 more

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Fiona PoyerDepartment of Pediatric Hematology and Oncology, St. Anna Children's Hospital Medical University of Vienna Vienna Austria.
Karin DieckmannDepartment of Radiotherapy Medical University of Vienna Vienna Austria.
Michael DworzakDepartment of Pediatric Hematology and Oncology, St. Anna Children's Hospital Medical University of Vienna Vienna Austria.
Melanie TamesbergerDepartment of Pediatrics and Adolescent Medicine Kepler University Hospital Linz Linz Austria.
Oskar HaasSt. Anna Children's Cancer Research Institute (CCRI) Vienna Austria.
Neil JonesDepartment of Pediatrics and Adolescent Medicine University Clinics Salzburg Salzburg Austria.
Karin NebralLabdia Diagnostics Vienna Austria.
Stefan KöhrerDepartment of Pediatric Hematology and Oncology, St. Anna Children's Hospital Medical University of Vienna Vienna Austria.
Reinhard MoserDepartment of Pediatrics and Adolescent Medicine State Hospital Leoben Leoben Austria.
Gabriele KropshoferDivision of Pediatric Hematology and Oncology and Stem Cell Transplantation, Department of Pediatrics and Adolescent Medicine Medical University of Innsbruck Innsbruck Austria.
Christina PetersDepartment of Pediatric Hematology and Oncology, St. Anna Children's Hospital Medical University of Vienna Vienna Austria.
Christian UrbanDivision of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine Medical University of Graz Graz Austria.
Georg MannDepartment of Pediatric Hematology and Oncology, St. Anna Children's Hospital Medical University of Vienna Vienna Austria.
Ulrike PötschgerSt. Anna Children's Cancer Research Institute (CCRI) Vienna Austria.
Andishe AttarbaschiDepartment of Pediatric Hematology and Oncology, St. Anna Children's Hospital Medical University of Vienna Vienna Austria.ORCID https://orcid.org/0000-0002-9285-6898
Austrian Berlin‐Frankfurt‐Münster (BFM) Study Group
St Anna Children's Hospital · ATInnsbruck Medical University · ATKepler Universitätsklinikum · ATLudwig Boltzmann Institute Applied Diagnostics · ATMedical University of Graz · ATMedical University of Vienna · ATUniversity of Salzburg · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Second malignant neoplasms (SMN) after primary childhood acute lymphoblastic leukemia (ALL) are rare. Among 1487 ALL patients diagnosed between 1981 and 2010 in Austria, the 10-year cumulative incidence of an SMN was 1.1% ± 0.3%. There was no difference in the 10-year incidence of SMNs with regard to diagnostic-, response- and therapy-related ALL characteristics except for a significantly higher incidence in patients with leukocytes ≥50.0 G/L at ALL diagnosis (2.1% ± 1.0% vs. 0% for 20.0-50.0 G/L, and 1.0% ± 0.3% for < 20.0 G/L;

Indexed as

acute lymphoblastic leukemiaincidenceoutcomeradiotherapysecond malignant neoplasms

Identifiers

PMID36051012
PMCPMC9421960
OpenAlexW4281780367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.