Evidence map›Paper›PMID 36050692›Full record

ArticleCost effectiveness and resource allocation : C/E2022

Cost-utility analysis of total knee arthroplasty alone and in comparison with post-surgical rehabilitation and conservative treatment in the Republic of Kazakhstan.

Dinara Serikova-Esengeldina, Natalya Glushkova, Gulzada Abdushukurova, Akmaral Mussakhanova, Ainur Mukhamejanova, Zaituna Khismetova, Dmitry Bokov, Alexandr Ivankov, Maiya Goremykina, Yuliya Semenova

Open access · goldAbstract read
In one paragraph

Article in Cost effectiveness and resource allocation : C/E, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Dinara Serikova-EsengeldinaDepartment of Public Health, Semey Medical University, Semey, Kazakhstan.
Natalya GlushkovaFaculty of Medicine and Healthcare, Al-Farabi Kazakh National University, Almaty, Kazakhstan.
Gulzada AbdushukurovaInstitute of Higher Medical Postgraduate Education, Akhmet Yassawi University, Turkestan, Kazakhstan.
Akmaral MussakhanovaDepartment of Public Health and Management, Astana Medical University, Nur-Sultan, Kazakhstan.
Ainur MukhamejanovaDepartment of Family Medicine #2, Astana Medical University, Nur-Sultan, Kazakhstan.
Zaituna KhismetovaDepartment of Public Health, Semey Medical University, Semey, Kazakhstan.
Dmitry BokovInstitute of Pharmacy, Sechenov First Moscow State Medical University, Moscow, Russia.
Alexandr IvankovIndependent Researcher, Almaty, Kazakhstan.
Maiya GoremykinaDepartment of Rheumatology and Noncommunicable Diseases, Semey Medical University, Semey, Kazakhstan.
Yuliya SemenovaSchool of Medicine, Nazarbayev University, Nur-Sultan, Kazakhstan. yumsem@mail.ru.ORCID http://orcid.org/0000-0003-1324-7806
Semey Medical University · KZAstana Medical University · KZAhmet Yesevi University · KZAl-Farabi Kazakh National University · KZGlobal Health Research Center of Central Asia · KZNazarbayev University · KZSechenov University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite ample international knowledge on cost-effectiveness of total knee arthroplasty (TKA), it has never been a subject of investigation in Kazakhstan or other post-Soviet economies. Our study aimed to carry-out the cost-utility analysis of TKA alone and in comparison with post-surgical rehabilitation and conservative treatment at health care facilities of Kazakhstan.

methodsTwo hundred and forty four patients with knee osteoarthritis (KOA) who underwent TKA in orthopedic departments of Almaty, Nur-Sultan and Semey hospitals between January 1, 2019 and September 30, 2019 were followed-up for 12 months. The health-related quality of life was measured by the EQ-5D utility and Western Ontario and McMaster Universities Osteoarthritis Index was used to measure the patients' health status. The costs were estimated from the view of health care provider. We calculated the cost per QALY, the Cost-Utility Ratio and the Incremental Cost-Effectiveness Ratio.

resultsAt the time of 12-month follow-up patients who received TKA alone or with the course of rehabilitation showed benefit over patients from the group of conservative treatment in terms of overall health status. Mean QALY gained at 12 months constituted 1.66 for the group that received TKA with rehabilitation, 1.48 for the group that received TKA alone and 0.24 for the group that received conservative treatment. Mean cost per QALY gained was USD 30 795.75 for KOA patients under conservative treatment, USD 6 323.69 for KOA patients subjected to TKA and USD 2 670.32 for KOA patients with rehabilitation course after TKA.

conclusionBoth TKA and TKA with rehabilitation could be considered as highly cost-effective interventions. The data obtained could be of interest for policy makers, medical professionals and KOA patients.

Indexed as

Cost analysisCost-utility ratioIncremental cost-effectiveness ratioQALYTotal knee arthroplasty

Identifiers

PMID36050692
PMCPMC9438142
OpenAlexW4294024805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.