Evidence map›Paper›PMID 36050603›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2022

Potentially inappropriate medications according to PRISCUS list and FORTA (Fit fOR The Aged) classification in geriatric psychiatry: a cross-sectional study.

Martin Schulze Westhoff, Adrian Groh, Sebastian Schröder, Phileas Johannes Proskynitopoulos, Kirsten Jahn, Martin Klietz, Benjamin Krichevsky, Dirk O Stichtenoth, Felix Wedegärtner, Stefan Bleich and 2 more

Abstract read
In one paragraph

Article in Journal of neural transmission (Vienna, Austria : 1996), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Sedatives and analgesics are major contributors to potentially inappropriate duplicate prescriptions in geriatric psychiatry.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Martin Schulze Westhoff *Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. schulzewesthoff.martin@mh-hannover.de.ORCID 0000-0003-3262-8137
Adrian Groh *Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.ORCID 0000-0002-4407-3557
Sebastian SchröderDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.ORCID 0000-0003-0905-274X
Phileas Johannes ProskynitopoulosDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.ORCID 0000-0003-1656-8867
Kirsten JahnDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.ORCID 0000-0002-2760-1602
Martin KlietzDepartment of Neurology, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-3054-9905
Benjamin KrichevskyMedical Service of the German Armed Forces, Kiel, Germany.ORCID 0000-0001-5899-0113
Dirk O StichtenothInstitute for Clinical Pharmacology, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-6526-0917
Felix WedegärtnerDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.ORCID 0000-0002-6171-4328
Stefan BleichDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.ORCID 0000-0001-5004-3824
Helge FrielingDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.ORCID 0000-0001-5146-9720
Johannes HeckInstitute for Clinical Pharmacology, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-5382-3014

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adverse drug reactions (ADRs) constitute a frequent cause of hospitalization in older people. The risk of ADRs is increased by the prescription of potentially inappropriate medications for older people (PIMs). The PRISCUS list and the FORTA classification represent established tools to detect PIMs. The aim of the present study was to examine the prevalence and characteristics of PIM prescriptions on the gerontopsychiatric ward of a university hospital in Germany. To this aim, medication charts of 92 patients (mean age 75.9 ± 7.7 years; 66.3% female) were analyzed on a weekly basis until patient discharge by utilization of the PRISCUS list and the FORTA classification. Overall, 335 medication reviews comprising 2363 drug prescriptions were analyzed. 3.0% of the prescribed drugs were PIMs according to the PRISCUS list, with benzodiazepines and Z-drugs accounting for nearly half (49.3%) of all PIM prescriptions. 30.4% of the patients were prescribed at least one PRISCUS-PIM, while 43.5% of the study population took at least one FORTA class D drug. A considerable proportion of gerontopsychiatric patients were affected by PIMs; however, the overall number of PIM prescriptions in the study population was low. Further improvements in the quality of prescribing should target the use of sedating agents such as benzodiazepines and Z-drugs. Physicians should be aware of discrepancies between the PRISCUS list and the FORTA classification.

Indexed as

Drug-Related Side Effects and Adverse ReactionsPotentially Inappropriate Medication ListAgedAged, 80 and overBenzodiazepinesCross-Sectional StudiesFemaleGeriatric PsychiatryHumansInappropriate PrescribingMaleBenzodiazepinesFORTAGeriatric psychiatryPharmacotherapy safetyPotentially inappropriate medicationsPRISCUS

Identifiers

PMID36050603
PMCPMC9550757

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.