Evidence map›Paper›PMID 36050365›Full record

ArticleScientific reports2022

Molecular characterization of multi drug resistant Escherichia coli isolates at a tertiary hospital in Abuja, Nigeria.

Nubwa Medugu, Mabel Kamweli Aworh, Kenneth Iregbu, Philip Nwajiobi-Princewill, Khadija Abdulraheem, Dawn M Hull, Lyndy Harden, Pallavi Singh, Stephen Obaro, Abiodun Egwuenu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Antimicrobial Activity ofAntibiotics (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. Antimicrobial Resistance in DiverseAntibiotics (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Antimicrobial agents and chemotherapy · 2024
    Review
  17. Article
  18. Article
  19. Molecular Epidemiology ofMicroorganisms · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Nubwa MeduguDepartment of Medical Microbiology, National Hospital Abuja, Abuja, Nigeria. nubwa.medugu@gmail.com.
Mabel Kamweli AworhDepartment of Veterinary and Pest Control Services, Federal Ministry of Agriculture and Rural Development, Abuja, Nigeria.
Kenneth IregbuDepartment of Medical Microbiology, National Hospital Abuja, Abuja, Nigeria.
Philip Nwajiobi-PrincewillDepartment of Medical Microbiology, National Hospital Abuja, Abuja, Nigeria.
Khadija AbdulraheemDepartment of Medical Microbiology, National Hospital Abuja, Abuja, Nigeria.
Dawn M HullDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
Lyndy HardenDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
Pallavi SinghNorthern Illinois University, De Kalb, IL, USA.
Stephen ObaroUniversity of Nebraska Medical Center, Omaha, USA.
Abiodun EgwuenuNigeria Center for Disease Control, Abuja, Nigeria.
Siddhartha ThakurDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
National Hospital Abuja · NGNorth Carolina State University · USFederal Ministry of Agriculture and Rural Development · NGNigeria Centre for Disease Control · NGNorthern Illinois University · USUniversity of Nebraska Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections caused by multi-drug resistant Escherichia coli cause significant morbidity and mortality especially in developing countries. In this study, we describe the molecular characteristics of E. coli isolated from clinical specimens and the patients' outcomes. Phenotypic methods were used in the identification and antimicrobial susceptibility testing of E. coli from clinical specimens from a tertiary hospital in Abuja, Nigeria. Whole genome sequencing was used to describe the antimicrobial resistance genes, serotypes, sequence types/clonal complexes, and mobile genetic elements. The mean age of the patients was 20.3 years with 70.1% females and majority of isolates 75% from urine, 21% from blood cultures, and 3% each from cerebrospinal fluid and endo-cervical swabs. Of the 107 non-duplicate E. coli isolates, 101 (94.3%) were resistant to ampicillin, 95 (88.8%) to trimethoprim/sulfamethoxazole, 86 (80.4%) to ceftriaxone, 60 (56.1%) to gentamicin, and eight (7.5%) to meropenem. There were 102 (95.3%) isolates that were multi-drug resistant (MDR). Expression of Extended Spectrum Beta Lactamase (ESBL) phenotype was detected in 54 (50%) and bla

Indexed as

Drug Resistance, Multiple, BacterialEscherichia coliEscherichia coli InfectionsAnti-Bacterial Agentsbeta-LactamasesEscherichia coli ProteinsFemaleHumansMaleMicrobial Sensitivity TestsNigeriaTertiary Care CentersAnti-Bacterial Agentsbeta-LactamasesEscherichia coli Proteins

Identifiers

PMID36050365
PMCPMC9437016
OpenAlexW4294084851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.