Evidence map›Paper›PMID 36050320›Full record

ArticleScientific reports2022

Increased risk of abortion after frozen-thawed embryo transfer in women with polycystic ovary syndrome phenotypes A and D.

Qiumin Wang, Yanjun Zheng, Ping Li, Guanqun Zhang, Shanshan Gao, Ze Wang, Baozhen Hao, Yuhua Shi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Qiumin WangCenter for Reproductive Medicine, Shandong University, 44 Wenhuaxi Road, Jinan, 250012, China.
Yanjun ZhengCenter for Reproductive Medicine, Shandong University, 44 Wenhuaxi Road, Jinan, 250012, China.
Ping LiWomen and Children's Hospital, School of Medicine, Xiamen University, 10 Zhenhai Road, Xiamen, 361003, China.
Guanqun ZhangCenter for Reproductive Medicine, Shandong University, 44 Wenhuaxi Road, Jinan, 250012, China.
Shanshan GaoCenter for Reproductive Medicine, Shandong University, 44 Wenhuaxi Road, Jinan, 250012, China.
Ze WangCenter for Reproductive Medicine, Shandong University, 44 Wenhuaxi Road, Jinan, 250012, China.
Baozhen HaoShandong Provincial Maternal and Child Health Care Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yuhua ShiShandong Provincial Clinical Research Center for Reproductive Health, Shandong University, 44 Wenhuaxi Road, Jinan, 250012, China. shiyuhua2003@126.com.
Shandong University · CNChildren’s Hospital of Fudan University Xiamen Branch · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) is associated with adverse pregnancy outcomes, including an increased risk of abortion, premature delivery, and even neonatal outcomes. After removing the effect of COH on patients, studying the pregnancy outcomes of patients with different PCOS phenotypes after FET may better reflect the impact of different PCOS phenotypes on ART outcomes. Data of 8903 patients who underwent FET between January 2017 and October 2019 were retrospectively collected and evaluated. All patients were divided into a control group and four phenotype groups based on Rotterdam criteria. The main outcomes were pregnancy outcomes after FET. We found significantly higher abortion (P = 0.010) and lower ongoing pregnancy (P = 0.023) rates for women with PCOS phenotypes A and D compared to those in the control group. After adjusting for potential confounders, PCOS phenotypes A and D were associated with an elevated risk of abortion (adjusted OR, 1.476, P = 0.016; adjusted OR, 1.348, P = 0.008, respectively). The results of this study suggest that when performing FET, clinicians should individually manage women with PCOS phenotypes A and D to reduce the rate of abortion and increase the rate of LB, and achieve better pregnancy outcomes.

Indexed as

Abortion, SpontaneousPolycystic Ovary SyndromeEmbryo TransferFemaleFertilization in VitroHumansPhenotypePregnancyPregnancy OutcomePregnancy RateRetrospective Studies

Identifiers

PMID36050320
PMCPMC9436971
OpenAlexW4294032042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.