Evidence map›Paper›PMID 36050143›Full record

ArticleBrachytherapy

3D-printed Magnetic Resonance (MR)-based gynecological phantom for image-guided brachytherapy training.

Carmen Kut, Tracy Kao, Marc Morcos, Younsu Kim, Emad Boctor, Akila N Viswanathan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brachytherapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carmen KutDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD.
Tracy KaoCarle Illinois College of Medicine, University of Illinois Urbana-Champaign, Champaign, IL.
Marc MorcosDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD.
Younsu KimWhiting School of Engineering, Johns Hopkins University, Baltimore, MD.
Emad BoctorWhiting School of Engineering, Johns Hopkins University, Baltimore, MD.
Akila N ViswanathanDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD. Electronic address: anv@jhu.edu.

Funding

Multiparametric Magnetic Resonance Imaging as a Novel Approach to Brachytherapy for Cervical CancerR01CA237005 · NCI · JOHNS HOPKINS UNIVERSITY · PI VISWANATHAN, AKILA · 2020 to 2024
$2.8M
NCI NIH HHS R01 CA237005
6 · The paper itself

Abstract

PURPOSE/

objectivesThere is a clinical need to develop anatomic phantoms for simulation-based learning in gynecological brachytherapy. Here, we provide a step-by-step approach to build a life-sized gynecological training phantom based on magnetic resonance imaging (MRI) of an individual patient. Our hypothesis is that this phantom can generate convincing ultrasound (US) images that are similar to patient scans.

methodsOrgans-at-risk were manually segmented using patient scans (MRI). The gynecological phantom was constructed using positive molds from 3D printing and polyvinyl chloride (PVC) plastisol. Tissue texture/acoustic properties were simulated using different plastic softener/hardener ratios and microbead densities. Nine readers (residents) were asked to evaluate 10 cases (1 ultrasound image per case) and categorize each as a "patient" or "phantom" image. To evaluate whether the phantom and patient images were equivalent, we used a multireader, multicase equivalence study design with two composite null hypotheses with proportion (p

resultsReaders correctly classified "patient" and "phantom" scans at p

conclusionsWe have outlined a manufacturing process to create a life-sized, gynecological phantom that is compatible with multi-modality imaging and can be used to simulate clinical scenarios in image-guided brachytherapy procedures.

Indexed as

BrachytherapyHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyPhantoms, ImagingTomography, X-Ray ComputedCT/MR safe phantomGynecological brachytherapyGynecologic malignanciesSimulation-based trainingUltrasound phantom

Identifiers

PMID36050143
PMCPMC10810234

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.