Evidence map›Paper›PMID 36049970›Full record

ArticleTrends in pharmacological sciences2022

A pharmacological strategy to recapitulate exercise-induced antitumoral immunity.

Amélie Rébillard, Jacques A Nunès, Alice Carrier

Open access · greenAbstract readComment
PubMed Publisher
In one paragraph

Article in Trends in pharmacological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Amélie RébillardM2S-EA7470, University of Rennes, Rennes, France; Institut Universitaire de France (IUF), Paris, France; French Network for Nutrition and Cancer Research (NACRe network), Jouy-en-Josas, France. Electronic address: amelie.rebillard@univ-rennes2.fr.
Jacques A NunèsFrench Network for Nutrition and Cancer Research (NACRe network), Jouy-en-Josas, France; Aix Marseille Univ, Inserm, CNRS, Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille (CRCM), Marseille, France. Electronic address: jacques.nunes@inserm.fr.
Alice CarrierFrench Network for Nutrition and Cancer Research (NACRe network), Jouy-en-Josas, France; Aix Marseille Univ, Inserm, CNRS, Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille (CRCM), Marseille, France. Electronic address: alice.carrier@inserm.fr.
Centre National de la Recherche Scientifique · FRInstitut Universitaire de France · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antitumor activity of exercise by means of enhanced immune activation is documented, but better identification of the underlying mechanisms is required to develop new therapeutic strategies. Recent work from the Dr Bar-Sagi group reveals that exercise engages IL-15 signaling and pharmacological activation of the IL-15/IL-15R axis mimics the exercise-driven immune cell-mediated cytotoxicity in pancreatic cancer.

Indexed as

Interleukin-15Signal TransductionHumansInterleukin-15IL-15 superagonistimmunologypancreatic cancerphysical activity

Identifiers

PMID36049970
OpenAlexW4293769490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.