Evidence map›Paper›PMID 36049674›Full record

ArticleContemporary clinical trials2022

A digital approach to asthma self-management in adults: Protocol for a pragmatic randomized controlled trial.

Jordan Silberman, Siavash Sarlati, Bronwyn Harris, Warris Bokhari, Homer Boushey, Asha Chesnutt, Peter Zhu, Kelly Sitts, Thomas H Taylor, Vincent J Willey and 9 more

Registry-linked trialOpen access · hybridAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04609644 (Digital Tools for Improved Awareness and Self-Management of Asthma in Adults), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04609644 nacompletednot on this map

Digital Tools for Improved Awareness and Self-Management of Asthma in Adults

TypeinterventionalSponsorElevance HealthRan2020 to 2023Enrolled901ConditionsAsthmaArmsDigital Tools for Asthma Self-Management
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Adoption of Digital Therapeutics in Europe.Therapeutics and clinical risk management · 2024
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Jordan SilbermanCarelon Digital Platforms, Elevance Health, Palo Alto, CA, USA. Electronic address: jordan.silberman@carelon.com.
Siavash SarlatiCarelon Digital Platforms, Elevance Health, Palo Alto, CA, USA; Department of Emergency Medicine, School of Medicine, University of California, San Francisco, USA. Electronic address: siavash.sarlati@carelon.com.
Bronwyn HarrisApple Inc, Cupertino, CA, USA.
Warris BokhariCarelon Digital Platforms, Elevance Health, Palo Alto, CA, USA.
Homer BousheySchool of Medicine, University of California, San Francisco, USA.
Asha ChesnuttApple Inc, Cupertino, CA, USA.
Peter ZhuApple Inc, Cupertino, CA, USA.
Kelly SittsCarelon Digital Platforms, Elevance Health, Palo Alto, CA, USA.
Thomas H TaylorDepartment of Epidemiology, University of California, Irvine, USA.
Vincent J WilleyHealthCore, Inc., Wilmington, DE, USA.
Emmanuel FuentesCarelon Digital Platforms, Elevance Health, Palo Alto, CA, USA.
Matthew LeKreyCarelon Digital Platforms, Elevance Health, Palo Alto, CA, USA.
Evan HouCarelon Digital Platforms, Elevance Health, Palo Alto, CA, USA.
Manpreet KaurCarelon Digital Platforms, Elevance Health, Palo Alto, CA, USA.
Christian NiyonkuruCarelon Digital Platforms, Elevance Health, Palo Alto, CA, USA.
Guido MuscioniCarelon Digital Platforms, Elevance Health, Chicago, IL, USA.
Matt T BianchiApple Inc, Cupertino, CA, USA.
Daniela A BotaUCI Center for Clinical Research and Department of Neurology, UC Irvine School of Medicine, Irvine, CA, USA.
Richard A LeeDivision of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, UC Irvine School of Medicine, Irvine, CA, USA.
Apple (United States) · USUniversity of California, Irvine · USUniversity of California, San Francisco · USWilmington University · US

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
NCI NIH HHS P30 CA062203
6 · The paper itself

Abstract

Asthma self-management can improve symptom control, but adherence to established self-management behaviors is often poor. With adult asthma uncontrolled in over 60% of U.S. cases, there is a need for scalable, cost-effective tools to improve asthma outcomes. Here we describe a protocol for the Asthma Digital Study, a 24-month, decentralized, pragmatic, open-label, randomized controlled trial investigating the impact of a digital asthma self-management (DASM) program on asthma outcomes in adults. The program leverages consumer-grade devices with a smartphone app to provide "smart nudges," symptom logging, trigger tracking, and other features. Participants are recruited (target N = 900) from throughout the U.S., and randomized to a DASM or control arm (1:1). Co-primary outcomes at one year are a) asthma-associated costs for acute care and b) change from baseline in Asthma Control Test™ scores. Findings may inform decisions around adoption of digital tools for asthma self-management. Trial registration:clinicaltrials.gov identifier: NCT04609644. Registered: Oct 30, 2020.

Indexed as

AsthmaMobile ApplicationsSelf-ManagementAdultCritical CareHumansMonitoring, PhysiologicPragmatic Clinical Trials as TopicRandomized Controlled Trials as TopicAsthmaDigital healthDigital therapeuticsWearable electronic devices

Identifiers

PMID36049674
PMCPMC12582168
OpenAlexW4293523264

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.