Evidence map›Paper›PMID 36049485›Full record

ArticleThe Journal of organic chemistry2022

Reduction of Substituted Benzo-Fused Cyclic Sulfonamides with Mg-MeOH: An Experimental and Computational Study.

Aisha Khalifa, Robert Redmond, Goar Sánchez-Sanz, Paul Evans

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aisha KhalifaCentre for Synthesis and Chemical Biology, School of Chemistry, University College Dublin, Dublin D04 N2E5, Ireland.
Robert RedmondCentre for Synthesis and Chemical Biology, School of Chemistry, University College Dublin, Dublin D04 N2E5, Ireland.ORCID 0000-0002-2963-829X
Goar Sánchez-SanzCentre for Synthesis and Chemical Biology, School of Chemistry, University College Dublin, Dublin D04 N2E5, Ireland.ORCID 0000-0002-1390-4004
Paul EvansCentre for Synthesis and Chemical Biology, School of Chemistry, University College Dublin, Dublin D04 N2E5, Ireland.ORCID 0000-0002-0584-876X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A study involving the use of Mg-MeOH for the double reductive cleavage of both N-S and C-S bonds in a series of 11 benzo-fused cyclic sulfonamides is reported. Examples where the sulfonamide nitrogen atom is part of a pyrrolidine ring effectively undergo reduction, as long as a methoxy substituent is not

Indexed as

MethanolSulfonamidesDeuteriumIndolesNitrogenPyrrolesPyrrolidinesSulfanilamideDeuteriumIndolesMethanolNitrogenPyrrolesPyrrolidinesSulfanilamideSulfonamides

Identifiers

PMID36049485
PMCPMC9486945

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.