Evidence map›Paper›PMID 36049063›Full record

ArticleAmerican journal of physiology. Renal physiology2022

Exogenous pericyte delivery protects the mouse kidney from chronic ischemic injury.

Turun Song, Xiang-Yang Zhu, Alfonso Eirin, Yamei Jiang, James D Krier, Hui Tang, Kyra L Jordan, Amir Lerman, Lilach O Lerman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Turun SongDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.
Xiang-Yang ZhuDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.
Alfonso EirinDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.
Yamei JiangDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.
James D KrierDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.
Hui TangDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.
Kyra L JordanDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.
Amir LermanDepartment of Cardiovascular diseases, Mayo Clinic, Rochester, Minnesota.
Lilach O LermanDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic · US

Funding

Obesity-induced dysfunction of human MSC in peripheral microvascular repairR01HL158691 · NHLBI · MAYO CLINIC ROCHESTER · PI Alfonso Eirin, Lilach O Lerman · 2022 to 2026
$3.4M
Obesity-induced mesenchymal stem cell senescenceR01DK120292 · NIDDK · MAYO CLINIC ROCHESTER · PI LERMAN, LILACH O · 2019 to 2022
$2.6M
Quantitative magnetization transfer MRI for evaluation of renal fibrosisR01DK122734 · NIDDK · MAYO CLINIC ROCHESTER · PI LERMAN, LILACH O · 2020 to 2023
$2.2M
Noninvasive Evaluation of Renal Allograft Fibrosis by MRIR21AG062104 · NIA · MAYO CLINIC ROCHESTER · PI LERMAN, LILACH O · 2020 to 2021
$414k
Mitochondrial injury interferes with endogenous renal repair in experimental renovascular diseaseR03DK122137 · NIDDK · MAYO CLINIC ROCHESTER · PI EIRIN, ALFONSO · 2019 to 2020
$239k
NHLBI NIH HHS R01 HL158691NIA NIH HHS R21 AG062104NIDDK NIH HHS R01 DK120292NIDDK NIH HHS R01 DK122734NIDDK NIH HHS R03 DK122137
6 · The paper itself

Abstract

Pericytes are considered reparative mesenchymal stem cell-like cells, but their ability to ameliorate chronic ischemic kidney injury is unknown. We hypothesized that pericytes would exhibit renoprotective effects in murine renal artery stenosis (RAS). Porcine kidney-derived pericytes (5 × 10

Indexed as

Graft vs Host DiseaseRenal Artery ObstructionAnimalsAtrophyCytokinesFibrosisInflammationKidneyMicePericytesSwineCytokinesfibrosisinflammationischemic injurykidneypericyte

Identifiers

PMID36049063
PMCPMC9602803
OpenAlexW4294190380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.