Evidence map›Paper›PMID 36048960›Full record

ArticleScience (New York, N.Y.)2022

Insulin signaling in the long-lived reproductive caste of ants.

Hua Yan, Comzit Opachaloemphan, Francisco Carmona-Aldana, Giacomo Mancini, Jakub Mlejnek, Nicolas Descostes, Bogdan Sieriebriennikov, Alexandra Leibholz, Xiaofan Zhou, Long Ding and 3 more

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 73 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. The pace and shape of ant ageing.Biological reviews of the Cambridge Philosophical Society · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Multi-Omics Analysis RevealsEcology and evolution · 2025
    Article
  17. Article
  18. Article
  19. From Egg to Adult: A Developmental Table of the Ant Monomorium pharaonis.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2024
    Article
  20. Juvenile hormone as a key regulator for asymmetric caste differentiation in ants.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Hua Yan *Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-6516-3287
Comzit Opachaloemphan *Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-2886-5586
Francisco Carmona-Aldana *Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-6785-9504
Giacomo ManciniDepartment of Biology, New York University, New York, NY 10003, USA.
Jakub MlejnekDepartment of Biology, New York University, New York, NY 10003, USA.
Nicolas DescostesDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-5599-5808
Bogdan SieriebriennikovDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-2948-7292
Alexandra LeibholzDepartment of Biology, New York University, New York, NY 10003, USA.
Xiaofan ZhouGuangdong Province Key Laboratory of Microbial Signals and Disease Control, South China Agricultural University, Guangzhou 510642, China.
Long DingDepartment of Biology, New York University, New York, NY 10003, USA.ORCID 0000-0001-7877-6878
Maria TraficanteDepartment of Biology, New York University, New York, NY 10003, USA.ORCID 0000-0003-3403-0489
Claude DesplanDepartment of Biology, New York University, New York, NY 10003, USA.ORCID 0000-0002-6914-1413
Danny ReinbergDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-4288-2016
New York University · USHoward Hughes Medical Institute · USSouth China Agricultural University · CN

Funding

Interdisciplinary Training Program Muscle BiologyT32AR007592 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI Aikaterini Kontrogianni-Konstantopoulos · 1996 to 2026
$11.7M
Stochastic choices in the retina and optic lobesR01EY013010 · NEI · NEW YORK UNIVERSITY · PI DESPLAN, CLAUDE · 1999 to 2025
$9.1M
Aging and rejuvenation: An ant model to study the regulation of longevityR01AG058762 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Claude Desplan, DANNY REINBERG · 2018 to 2026
$6.2M
Reinforcement of epigenetic memory by social interactions in antsR21GM114457 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REINBERG, DANNY · 2014 to 2014
$254k
Regulation of variable lifespan in castes of antsF32AG044971 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI YAN, HUA · 2013 to 2015
$165k
Howard Hughes Medical InstituteNEI NIH HHS R01 EY013010NIAMS NIH HHS T32 AR007592NIA NIH HHS F32 AG044971NIA NIH HHS R01 AG058762NIGMS NIH HHS R21 GM114457
6 · The paper itself

Abstract

In most organisms, reproduction is correlated with shorter life span. However, the reproductive queen in eusocial insects exhibits a much longer life span than that of workers. In

Indexed as

AntsInsulinLongevityReproductionAnimalsFemaleMitogen-Activated Protein Kinase KinasesOvarySignal TransductionVitellogeninsInsulinMitogen-Activated Protein Kinase KinasesVitellogenins

Identifiers

PMID36048960
PMCPMC9526546
OpenAlexW4294073636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.