ArticleScience (New York, N.Y.)2022
Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling.
Abstract read
In one paragraph
Article in Science (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed.
- Harnessing Natural Diversity and Rational Design for Enhanced Plant Immunity.Plant, cell & environment · 2026Review
- Mechanisms and balanced regulation of plant immunity.Nature reviews. Molecular cell biology · 2026Review
- Phage-encoded NARP3 system rebuilds NADScience advances · 2026Article
- Review
- dITP-induced remodeling activates the filamentous effector complex in Kongming anti-phage defense.Nature communications · 2026Article
- Synthetically designed anti-defense proteins overcome barriers to bacterial transformation and phage infection.Nature communications · 2026Article
- Functional diversity of phage sponge proteins that sequester host immune signals.Nature microbiology · 2026Article
- Phage RyR-domain proteins degrade ADPR-based immune signals and fuel NADbioRxiv : the preprint server for biology · 2026Article
- Article
- Chemical inactivation of a bacterial immune system de-domesticates a temperate phage and promotes its spread.bioRxiv : the preprint server for biology · 2026Article
- TIR-like NADases act in bacterial immunity and the RNA vault.bioRxiv : the preprint server for biology · 2026Article
- Chemical suppression of a bacterial immune system revives repressed phages.bioRxiv : the preprint server for biology · 2026Article
- Plant NLRs are getting into higher-order architectures.The Plant journal : for cell and molecular biology · 2026Review
- Rapid Discovery of CD38 Inhibitor via DNA-Encoded Natural Product Library Screening.Molecules (Basel, Switzerland) · 2026Article
- Changes in Metabolism and Lipid Composition with Nitrogen Starvation and Recovery in a New Productive Strain ofInternational journal of molecular sciences · 2026Article
- Chemical inhibition of a bacterial immune system.Cell host & microbe · 2026Article
- Molecular mechanisms of plant NLR activation and signalling.The Plant journal : for cell and molecular biology · 2026Review
- From gene-for-gene to NLRome-for-effectorome: decoding the dynamic interplay between phytopathogenic effector networks and plant immune systems.FEMS microbiology reviews · 2026Review
- TIR innovations in plant immunity.The New phytologist · 2026Review
- Manipulation of the nucleotide pool in human, bacterial and plant immunity.Nature reviews. Immunology · 2026Review
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors.
Mohammad K Manik *School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0001-9510-2250
Yun Shi *Institute for Glycomics, Griffith University, Southport, QLD 4222, Australia.ORCID 0000-0003-3365-4679
Sulin Li *School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-6116-4362
Mark A ZaydmanDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63100, USA.ORCID 0000-0002-4236-1459
Neha DamarajuDepartment of Developmental Biology, Washington University School of Medicine in St. Louis, St. Louis, MO 63100, USA.
Samuel EastmanDepartment of Plant Pathology, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.ORCID 0000-0003-1550-0828
Thomas G SmithDepartment of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID 0000-0003-1366-8053
Weixi GuSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-1185-3557
Veronika MasicInstitute for Glycomics, Griffith University, Southport, QLD 4222, Australia.
Tamim MosaiabInstitute for Glycomics, Griffith University, Southport, QLD 4222, Australia.ORCID 0000-0002-8251-0180
James S WeagleyEdison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.ORCID 0000-0001-5050-773X
Steven J HancockSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Eduardo VasquezInstitute for Glycomics, Griffith University, Southport, QLD 4222, Australia.ORCID 0000-0002-5520-3070
Lauren Hartley-TassellInstitute for Glycomics, Griffith University, Southport, QLD 4222, Australia.ORCID 0000-0003-2415-0321
Nestoras KargiosSchool of Life Sciences, University of Warwick, Coventry CV4 7AL, UK.ORCID 0000-0003-0856-062X
Natsumi MarutaSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-6246-6346
Bryan Y J LimSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-0554-909X
Hayden BurdettSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0003-4803-9660
Michael J LandsbergSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-2464-990X
Mark A SchembriSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0003-4863-9260
Ivan ProkesDepartment of Chemistry, University of Warwick, Coventry CV4 7AL, UK.ORCID 0000-0003-3896-8941
Lijiang SongDepartment of Chemistry, University of Warwick, Coventry CV4 7AL, UK.ORCID 0000-0002-5843-005X
Murray GrantSchool of Life Sciences, University of Warwick, Coventry CV4 7AL, UK.ORCID 0000-0003-3357-0264
Aaron DiAntonioDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63100, USA.ORCID 0000-0002-7262-0968
Jeffrey D NansonSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0003-1306-1948
Ming GuoDepartment of Agronomy and Horticulture, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Jeffrey MilbrandtDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63100, USA.ORCID 0000-0002-5477-7689
Thomas VeInstitute for Glycomics, Griffith University, Southport, QLD 4222, Australia.ORCID 0000-0002-0113-1905
Bostjan KobeSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0001-9413-9166
Funding
DISSECTION OF SARM1-INDUCED AXON DEGENERATION AND CELL DEATHR01NS087632 · NINDS · WASHINGTON UNIVERSITY · PI Aaron Diantonio, JEFFREY D MILBRANDT · 2014 to 2026
$6.4MBiotechnology and Biological Sciences Research Council BB/D007046/1NINDS NIH HHS R01 NS087632
Abstract
Cyclic adenosine diphosphate (ADP)-ribose (cADPR) isomers are signaling molecules produced by bacterial and plant Toll/interleukin-1 receptor (TIR) domains via nicotinamide adenine dinucleotide (oxidized form) (NAD
Indexed as
Adaptor Proteins, Vesicular TransportADP-ribosyl CyclaseBacteriaBacterial ProteinsCyclic ADP-RibosePlant ImmunityToll-Like ReceptorsIsomerismNADProtein DomainsReceptors, Interleukin-1Signal TransductionTryptophanAdaptor Proteins, Vesicular TransportADP-ribosyl CyclaseBacterial ProteinsCyclic ADP-RiboseNADReceptors, Interleukin-1Toll-Like ReceptorsTryptophan
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.