Evidence map›Paper›PMID 36048812›Full record

ArticlePloS one2022

Balance dysfunction the most significant cause of in-hospital falls in patients taking hypnotic drugs: A retrospective study.

Ryuki Hashida, Hiroo Matsuse, Shinji Yokoyama, Sayuri Kawano, Eriko Higashi, Hiroshi Tajma, Masafumi Bekki, Sohei Iwanaga, Koji Hara, Yosuke Nakamura and 6 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Ryuki HashidaDepartment of Orthopaedics, Kurume University, Kurume University School of Medicine, Kurume, Japan.ORCID 0000-0002-2459-9949
Hiroo MatsuseDepartment of Orthopaedics, Kurume University, Kurume University School of Medicine, Kurume, Japan.
Shinji YokoyamaDivision of Cardiovascular Medicine, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan.
Sayuri KawanoDepartment of Nursing, Kurume University Hospital, Kurume, Fukuoka, Japan.
Eriko HigashiDivision of Rehabilitation, Kurume University Hospital, Kurume, Fukuoka, Japan.
Hiroshi TajmaDepartment of Orthopaedics, Kurume University, Kurume University School of Medicine, Kurume, Japan.
Masafumi BekkiDepartment of Orthopaedics, Kurume University, Kurume University School of Medicine, Kurume, Japan.
Sohei IwanagaDepartment of Orthopaedics, Kurume University, Kurume University School of Medicine, Kurume, Japan.
Koji HaraDepartment of Orthopaedics, Kurume University, Kurume University School of Medicine, Kurume, Japan.
Yosuke NakamuraDepartment of Orthopaedics, Kurume University, Kurume University School of Medicine, Kurume, Japan.
Yuji KaneyukiDepartment of Orthopaedics, Kurume University, Kurume University School of Medicine, Kurume, Japan.
Takeshi NagoDepartment of Orthopaedics, Kurume University, Kurume University School of Medicine, Kurume, Japan.
Yoshihiro FukumotoDivision of Cardiovascular Medicine, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan.
Motohiro OzoneDepartment of Neuropsychiatry, Kurume University School of Medicine, Kurume, Japan.
Naohisa UchimuraDepartment of Neuropsychiatry, Kurume University School of Medicine, Kurume, Japan.
Naoto ShibaDepartment of Orthopaedics, Kurume University, Kurume University School of Medicine, Kurume, Japan.
Kurume University · JPKurume University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePreventing falls in patients is one of the most important concerns in acute hospitals. Balance disorder and hypnotic drugs lead to falls. The Standing Test for Imbalance and Disequilibrium (SIDE) is developed for the evaluation of static standing balance ability. There have been no reports of a comprehensive assessment of falls risk including hypnotic drugs and SIDE. The purpose of this study was to investigate the fall rate of each patient who took the hypnotic drug and the factor associated with falls.

methodsFall rates for each hypnotic drug were calculated as follows (number of patients who fell/number of patients prescribed hypnotic drug x 100). We investigated the hypnotic drugs as follows; benzodiazepine drugs, Z-drugs, melatonin receptor agonists, and orexin receptor antagonists. Hypnotic drug fall rate was analyzed using Pearson's chi-square test. Decision tree analysis is the method we used to discover the most influential factors associated with falls.

resultsThis study included 2840 patients taking hypnotic drugs. Accidents involving falls were reported for 211 of inpatients taking hypnotic drugs. Z-drug recipients had the lowest fall rate among the hypnotic drugs. We analyzed to identify independent factors for falls, a decision tree algorithm was created using two divergence variables. The SIDE levels indicating balance disorder were the initial divergence variable. The rate of falls in patients at SIDE level ≦ 2a was 14.7%. On the other hand, the rate of falls in patients at SIDE level ≧ 2b was 2.9%. Gender was the variable for the second classification. In this analysis, drugs weren't identified as divergence variables for falls.

conclusionThe SIDE balance assessment was the initial divergence variable by decision tree analysis. In order to prevent falls, it seems important not only to select appropriate hypnotic drugs but also to assess patients for balance and implement preventive measures.

Indexed as

Hypnotics and SedativesInpatientsHospitalsHumansRetrospective StudiesRisk FactorsHypnotics and Sedatives

Identifiers

PMID36048812
PMCPMC9436085
OpenAlexW4294044965

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.