Trial reportJournal of the American Heart Association2022
Alert-Triggered Patient Education Versus Nurse Feedback for Nonadministered Venous Thromboembolism Prophylaxis Doses: A Cluster-Randomized Controlled Trial.
Trial report in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Cystic fibrosis and sickle cell disease associated with nonadministration of VTE prophylaxis in hospitalized adults.Blood advances · 2026Article
- Effect of nurse informatics on medication errors, patients' satisfaction, and quality patient care - A systematic review and metanalysis.Journal of education and health promotion · 2026Review
- Implementing a Patient-Centered Education Bundle to Improve Venous Thromboembolism Prevention.JAMA surgery · 2025Article
- Inaccuracies of venous thromboembolism risk assessment and prevention practices among medically ill patients.Blood advances · 2025Article
- Evolution of an Electronic Health Record-Based Alert to Optimize Venous Thromboembolism Prophylaxis.Applied clinical informatics · 2025Article
- Venous thromboembolism prophylaxis for hospitalized adult patients: a survey of US health care providers on attitudes and practices.Research and practice in thrombosis and haemostasis · 2023Article
- A systematic approach to venous thromboembolism prevention: a focus on UK experience.Research and practice in thrombosis and haemostasis · 2023Article
Corrections and comments
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Authors and funding
18 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Many hospitalized patients are not administered prescribed doses of pharmacologic venous thromboembolism prophylaxis. Methods and Results In this cluster-randomized controlled trial, all adult non-intensive care units (10 medical, 6 surgical) in 1 academic hospital were randomized to either a real-time, electronic alert-triggered, patient-centered education bundle intervention or nurse feedback intervention to evaluate their effectiveness for reducing nonadministration of venous thromboembolism prophylaxis. Primary outcome was the proportion of nonadministered doses of prescribed pharmacologic prophylaxis. Secondary outcomes were proportions of nonadministered doses stratified by nonadministration reasons (patient refusal, other). To test our primary hypothesis that both interventions would reduce nonadministration, we compared outcomes pre- versus postintervention within each cohort. Secondary hypotheses were tested comparing the effectiveness between cohorts. Of 11 098 patient visits, overall dose nonadministration declined significantly after the interventions (13.4% versus 9.2%; odds ratio [OR], 0.64 [95% CI, 0.57-0.71]). Nonadministration decreased significantly (
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Registered trials
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