ArticleJournal of gynecologic oncology2022
Immunonutrition in ovarian cancer: clinical and immunological impact?
Article in Journal of gynecologic oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07210164 (Prehabilitation With Exercise and Immunonutrition), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prehabilitation With Exercise and Immunonutrition (Ocoxin®) in the Perioperative Management of Gynecologic Malignancies Under ERAS Protocol.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The role of nutritional supplementation in preventing postoperative complications: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Perioperative immunonutrition intervention on postoperative outcomes among gynaecological cancer patients under enhanced recovery after surgery setting.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Trial
- Postoperative Vaginal Cuff Healing After Minimally Invasive Surgery for Endometrial Cancer: The Role of Postoperative Immunonutrition.Journal of clinical medicine · 2026Article
- Anesthesia, analgesia, and immunonutrition in perioperative immune homeostasis: a focused mini review.Frontiers in nutrition · 2026Review
- The impact of preoperative immunonutritional status on postoperative complications in ovarian cancer.Journal of ovarian research · 2025Article
- Immunonutrition in ERAS Protocol for Patients with Gynecologic Cancer: A Narrative Review of the Literature.Life (Basel, Switzerland) · 2025Review
- Preoperative malnutrition predicts poor early immune recovery following gynecologic cancer surgery: a retrospective cohort study and risk nomogram development.Frontiers in immunology · 2025Article
- Development and Validation of a Prognostic Model for Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma Based on Preoperative Serum Prealbumin.Journal of hepatocellular carcinoma · 2023Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMalnutrition is frequent in ovarian cancer (OC) patients and may compromise post-operative outcomes. The aim of this study is to evaluate the impact of pre-operative immunonutrition on the surgical outcome of OC patients, and on their nutritional, inflammatory and peripheral blood immune status.
methodsA prospective study was performed between September 2016 and April 2020. Immune-enhancing enteral nutrition was administered to 42 patients before surgery according to their nutritional status assessed by the Malnutritional Universal Screening Tool. Biochemical and hematological monitoring was performed before and after immunonutrition. Post-operative outcomes were assessed and compared with those of a similar group of patients treated without nutritional support.
resultsOf the 42 immune-nourished patients, 23 (54.8%) had a low, 11 (26.2%) an intermediate and 8 (19%) a high risk of malnutrition. After the immunonutritional intake, significant variations of prealbumin, creatinine and white blood cells were detected. All T cell populations had an increasing trend, in particular CD3
conclusionPre-operative immunonutrition improves the surgical outcome of OC patients. After immunonutrition, an increase of CD3
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