Evidence map›Paper›PMID 36046558›Full record

ArticleIranian journal of parasitology

Treatment of Murine Toxoplasmosis with Oral and Parenteral Artemether and Following by Detection of

Hajar Mikaeiloo, Fatemeh Ghaffarifar, Abdolhossein Dalimi, Mohammad Zuhair Hassan, Zohreh Sharifi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hajar MikaeilooDepartment of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Fatemeh GhaffarifarDepartment of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Abdolhossein DalimiDepartment of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Mohammad Zuhair HassanDepartment of Immunology, Faculty of Medical Sciences, Tarbiat Modares University of Medical Sciences, Tehran, Iran.
Zohreh SharifiBlood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.
Tarbiat Modares University · IRHigh Institute for Education and Research in Transfusion Medicine · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: BALB/c mice were infected with tachyzoiets of Results: Both treatment with sulfadiazine and artemether showed significant prolongation in time to death of the infected mice compared to the control group. Median survival days for parenteral artemether, oral artemether, sulfadiazine and control group were 8, 11, 12 and 6 d respectively. Expression of B1 gene in liver and brain of mice after treatment with artemether and sulfadiazine were reduced in comparison to housekeeping gene (β-tubulin gene). The fold change (comparing to control group) for parenteral artemether, oral artemether, sulfadiazine is 0.034, 0.027 and 0.111 for liver and 0.220, 0.425 and 0.366 for brain respectively. Conclusion: Artemether is effective to control the tachyzoites of

Indexed as

ArtemetherBALB/c miceOralParenteralPolymerase chain reactionToxoplasma gondii

Identifiers

PMID36046558
PMCPMC9375721
OpenAlexW4223614045

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.