Evidence map›Paper›PMID 36046460›Full record

ArticleBioMed research international2022

lncRNA Vgll3 Regulates the Activated Proliferation of Mouse Myocardial Fibroblasts through TGF-

Bing Liu, Miao Chen, Wei Meng

RetractedOpen access · hybridAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Bing LiuDepartment of Emergency, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China.ORCID https://orcid.org/0000-0002-8647-3487
Miao ChenDepartment of Emergency, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China.ORCID https://orcid.org/0000-0001-6620-5488
Wei MengDepartment of Cardiology, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China.ORCID https://orcid.org/0000-0002-9761-8290
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac fibrosis is a risk factor leading to various cardiac diseases, and its mechanism has not been clarified. However, long noncoding RNA (lncRNA) can mediate the pathological process of cardiac fibrosis. Objective: This study is aimed at determining the pathological role of lncRNA Vgll3 in cardiac fibrosis and explore its potential mechanism. Methods: Myocardium fibroblasts (CFs) were isolated from mice and stimulated with angiotensin II (Ang-II). The expression of Vgll3 and transforming growth factor- Results: Upregulation of Vgll3 promoted the expression of TGF- Conclusion: Vgll3 can promote the activation and proliferation of CFs in mice by activating TGF-

Indexed as

RNA, Long NoncodingAnimalsCell ProliferationFibroblastsFibrosisMiceMyocardiumTransforming Growth Factor beta1Transforming Growth Factor beta3RNA, Long NoncodingTgfb3 protein, mouseTransforming Growth Factor beta1Transforming Growth Factor beta3

Identifiers

PMID36046460
PMCPMC9420582
OpenAlexW4292533905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.