ReviewFrontiers in cell and developmental biology2022
Evolution of astrocytes: From invertebrates to vertebrates.
Review in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Varicose projection astrocytes: Conserved reactive cells in brain pathology.Science advances · 2026Article
- A novel theory of rapid eye movement sleep as an integral component of the seasonal timekeeping apparatus.Frontiers in neuroscience · 2026Article
- Differential morphology and distribution of GFAP astrocytes in vocal brain circuit in a songbird Southern house wren and humans.Frontiers in neuroanatomy · 2026Article
- Shaping the Neocortex: Radial Glia and Astrocytes in Development and Evolution.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Conservation of glial density and cell-type ratios within a brain region across mammals.PNAS nexus · 2025Article
- From nociception in aneural animals to human suffering: toward a comparative biology of pain.The Journal of experimental biology · 2025Review
- Anatomical mapping of GFAP-immunoreactive astrocytes in the tree shrew brain.Zoological research · 2025Article
- Developmental roles of astrocytes in circuit wiring.Current opinion in neurobiology · 2025Review
- Species-specific blood-brain barrier permeability in amphibians.BMC biology · 2025Article
- Exploring neuroglial signaling: diversity of molecules implicated in microglia-to-astrocyte neuroimmune communication.Reviews in the neurosciences · 2025Review
- Review
- Astrocytes in aging.Neuron · 2025Review
- Beyond the canonical niche: how astrocytes carried neurogenic potential into the brain parenchyma.Frontiers in cell and developmental biology · 2025Review
- The relative withdrawal of GFAP-An essential component of brain evolution.Frontiers in neuroanatomy · 2025Article
- Advancing through the blood-brain barrier: mechanisms, challenges and drug delivery strategies.ADMET & DMPK · 2025Review
- Brain stars take the lead during critical periods of early postnatal brain development: relevance of astrocytes in health and mental disorders.Molecular psychiatry · 2024Review
- Spatial and single-nucleus transcriptomics decoding the molecular landscape and cellular organization of avian optic tectum.iScience · 2024Article
- Astrocytes of the Anterior Commissure Regulate the Axon Guidance Pathways of Newly Generated Neocortical Neurons in the OpossumInternational journal of molecular sciences · 2024Article
- Differences in vocal brain areas and astrocytes between the house wren and the rufous-tailed hummingbird.Frontiers in neuroanatomy · 2024Article
- Evolution of Astrocyte-Neuron Interactions Across Species.Advances in neurobiology · 2024Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The central nervous system (CNS) shows incredible diversity across evolution at the anatomical, cellular, molecular, and functional levels. Over the past decades, neuronal cell number and heterogeneity, together with differences in the number and types of neuro-active substances, axonal conduction, velocity, and modes of synaptic transmission, have been rigorously investigated in comparative neuroscience studies. However, astrocytes, a specific type of glial cell in the CNS, play pivotal roles in regulating these features and thus are crucial for the brain's development and evolution. While special attention has been paid to mammalian astrocytes, we still do not have a clear definition of what an astrocyte is from a broader evolutionary perspective, and there are very few studies on astroglia-like structures across all vertebrates. Here, I elucidate what we know thus far about astrocytes and astrocyte-like cells across vertebrates. This information expands our understanding of how astrocytes evolved to become more complex and extremely specialized cells in mammals and how they are relevant to the structure and function of the vertebrate brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.