Evidence map›Paper›PMID 36046174›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2022

Compilation of 10 Years of MIRU-VNTR Data: Canadian National Tuberculosis Laboratory's Experience.

Meenu K Sharma, Debra Janella, Alisa McGurran, Cindi Corbett, Heather Adam, Pierre-Marie Akochy, David Haldane, Hope MacKenzie, Jessica Minion, Robert Needle and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Insight into the genetic diversity ofMicrobiology spectrum · 2026
    Article
  2. Genetic Diversity and Molecular Epidemiology ofPathogens (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Meenu K SharmaNational Reference Centre for Mycobacteriology, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.ORCID https://orcid.org/0000-0002-6020-9995
Debra JanellaNational Reference Centre for Mycobacteriology, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Alisa McGurranNational Reference Centre for Mycobacteriology, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Cindi CorbettNational Reference Centre for Mycobacteriology, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Heather AdamShared Health, Winnipeg, Manitoba, Canada.
Pierre-Marie AkochyLaboratoire de Sante Publique du Quebec, Montreal, Quebec, Canada.
David HaldanePublic Health Laboratory Network, Halifax, Nova Scotia, Canada.
Hope MacKenzieAtlantic Health Sciences Corporation, Saint John, New Brunswick, Canada.
Jessica MinionSaskatchewan Health Authority, Saskatoon, Saskatchewan, Canada.
Robert NeedleNewfoundland and Labrador Public Health Laboratory, Saint John, Newfoundland, Canada.
Caroline NewberryOffice of Chief Public Health Officer, Yellowknife, Northwest Territories, Canada.
Michael PattersonGovernment of Nunavut, Iqaluit, Nunavut, Canada.
Inna SekirovBC Centre for Disease Control, Vancouver, British Columbia, Canada.
Gregory TyrrellAlberta Health Services, Edmonton, Alberta, Canada.ORCID https://orcid.org/0000-0002-5276-2416
Hafid SoualhineNational Reference Centre for Mycobacteriology, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Public Health Agency of Canada · CAAlberta Health Services · CABC Centre for Disease Control · CAGovernment of Northwest Territories · CAGovernment of Nunavut · CAInstitut National de Santé Publique du Québec · CAManitoba Health · CASaskatchewan Health Authority · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis is a significant cause of morbidity worldwide and is a priority at the provincial and federal levels in Canada. It is known that tuberculosis transmission networks are complex and span many years as well as different jurisdictions and countries. MIRU-VNTR is a universal tuberculosis genotyping method that utilizes a 24-loci pattern and it has shown promise in identifying inter and intrajurisdictional clusters within Canada. MIRU-VNTR data collected over 10 years from the National Reference Centre for Mycobacteriology (NRCM) were analyzed in this study. Some clusters were unique to a single province/territory, while others spanned multiple provinces and/or territories in Canada. The use of a universal laboratory test can enhance contact tracing, provide geographical information on circulating genotypes, and hence, aid in tuberculosis investigation by public health. The housing of all data on one platform, technical ease of the method, easy exchange of data between jurisdictions, and strong collaboration with laboratories and surveillance units at the provincial and federal levels have the potential to identify possible outbreaks in real time.

Identifiers

PMID36046174
PMCPMC9424012
OpenAlexW4294129414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.