Evidence map›Paper›PMID 36045965›Full record

Trial reportComputational intelligence and neuroscience2022

Effect of Loratadine Tablets in Combination with Other Drugs on Nasal Physiological Function and T Lymphocyte Subsets in Patients with Allergic Rhinitis.

Jie Zhang, Hongzheng Cheng, Yi Luo, Dan Kan, Yinghuai Wang

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Computational intelligence and neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jie ZhangPuRen Hospital Affiliated to Wuhan University of Science and Technolog/Otorhinolaryngology, No. 1 Benxi Street, Qingshan District, Wuhan City 430081, Hubei Province, China.
Hongzheng ChengPuRen Hospital Affiliated to Wuhan University of Science and Technolog/Otorhinolaryngology, No. 1 Benxi Street, Qingshan District, Wuhan City 430081, Hubei Province, China.
Yi LuoPuRen Hospital Affiliated to Wuhan University of Science and Technolog/Otorhinolaryngology, No. 1 Benxi Street, Qingshan District, Wuhan City 430081, Hubei Province, China.
Dan KanPuRen Hospital Affiliated to Wuhan University of Science and Technolog/Otorhinolaryngology, No. 1 Benxi Street, Qingshan District, Wuhan City 430081, Hubei Province, China.
Yinghuai WangPuRen Hospital Affiliated to Wuhan University of Science and Technolog/Otorhinolaryngology, No. 1 Benxi Street, Qingshan District, Wuhan City 430081, Hubei Province, China.ORCID https://orcid.org/0000-0001-6351-8016
Wuhan University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the effects of loratadine tablets in combination with other drugs on nasal physiological function and T lymphocyte subsets in patients with allergic rhinitis (AR). Methods: A total of 120 AR patients treated in our hospital from February 2018 to February 2021 were randomly divided into control group and research group. The control group was given mometasone furoate nasal spray combined with loratadine tablets, while the research group was given budesonide combined with loratadine. The efficacy, duration of clinical symptom remission, immune function indicators, T lymphocyte subset, nasal physiological function, and incidence of adverse reactions were compared between the two groups. Results: The efficacy results of the two groups showed that the effective rate of the research group was 96.67%, while the effective rate of the control group was 83.33%. The effective rate in the research group was higher compared to the control group ( Conclusion: Budesonide and loratadine are effective in improving patient efficacy, T lymphocyte subsets, and nasal physiological function, and are safer.

Indexed as

Anti-Allergic AgentsRhinitis, AllergicAdministration, IntranasalBudesonideHumansLoratadineTabletsT-Lymphocyte SubsetsAnti-Allergic AgentsBudesonideLoratadineTablets

Identifiers

PMID36045965
PMCPMC9420603
OpenAlexW4292560859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.