Evidence map›Paper›PMID 36045919›Full record

ArticleFrontiers in medicine2022

Calibration and validation of the Pneumonia Shock Score in critically ill patients with SARS-CoV-2 infection, a multicenter prospective cohort study.

Thomas A Carmo, Isabella B B Ferreira, Rodrigo C Menezes, Márcio L T Pina, Roberto S Oliveira, Gabriel P Telles, Antônio F A Machado, Tércio C Aguiar, Juliana R Caldas, María B Arriaga and 3 more

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Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Thomas A CarmoUniversidade Salvador (UNIFACS), Salvador, Bahia, Brazil.
Isabella B B FerreiraMultinational Organization Network Sponsoring Translational and Epidemiological Research Initiative, Salvador, Brazil.
Rodrigo C MenezesMultinational Organization Network Sponsoring Translational and Epidemiological Research Initiative, Salvador, Brazil.
Márcio L T PinaEscola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil.
Roberto S OliveiraEscola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil.
Gabriel P TellesEscola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil.
Antônio F A MachadoUniversidade Salvador (UNIFACS), Salvador, Bahia, Brazil.
Tércio C AguiarUniversidade Salvador (UNIFACS), Salvador, Bahia, Brazil.
Juliana R CaldasHospital São Rafael, Rede Dor, Salvador, Bahia, Brazil.
María B ArriagaMultinational Organization Network Sponsoring Translational and Epidemiological Research Initiative, Salvador, Brazil.
Kevan M AkramiMultinational Organization Network Sponsoring Translational and Epidemiological Research Initiative, Salvador, Brazil.
Nivaldo M Filgueiras FilhoUniversidade Salvador (UNIFACS), Salvador, Bahia, Brazil.
Bruno B AndradeUniversidade Salvador (UNIFACS), Salvador, Bahia, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prognostic tools developed to stratify critically ill patients in Intensive Care Units (ICUs), are critical to predict those with higher risk of mortality in the first hours of admission. This study aims to evaluate the performance of the pShock score in critically ill patients admitted to the ICU with SARS-CoV-2 infection. Methods: Prospective observational analytical cohort study conducted between January 2020 and March 2021 in four general ICUs in Salvador, Brazil. Descriptive statistics were used to characterize the cohort and a logistic regression, followed by cross-validation, were performed to calibrate the score. A ROC curve analysis was used to assess accuracy of the models analyzed. Results: Six hundred five adult ICU patients were included in the study. The median age was 63 (IQR: 49-74) years with a mortality rate of 33.2% (201 patients). The calibrated pShock-CoV score performed well in prediction of ICU mortality (AUC of 0.80 [95% Confidence Interval (CI): 0.77-0.83; Conclusions: The pShock-CoV score demonstrated robust discriminatory capacity and may assist in targeting scarce ICU resources during the COVID-19 pandemic to those critically ill patients most likely to benefit.

Indexed as

COVID-19critical caremortalityprognosisrisk factors

Identifiers

PMID36045919
PMCPMC9420902

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.