Evidence map›Paper›PMID 36045754›Full record

ArticleFrontiers in physiology2022

Multi-tissue transcriptional changes and core circadian clock disruption following intensive care.

Henry C Hollis, Julian N Francis, Ron C Anafi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Tumor circadian clock strength influences metastatic potential and predicts patient prognosis in luminal A breast cancer.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Henry C HollisSchool of Biomedical Engineering and Health Systems, Drexel University, Philadelphia, PA, United States.
Julian N FrancisDepartment of Mathematics, Howard University, Washington, DC, United States.
Ron C AnafiDivision of Sleep Medicine and Chronobiology and Sleep Institute, University of Pennsylvania, Philadelphia, PA, United States.
Drexel University · USHoward University · USSleepMed · US

Funding

Integrated Informatic and Experimental Evaluations of Cancer ChronotherapyR01CA227485 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ANAFI, RON C., HOGENESCH, JOHN B · 2019 to 2023
$3.0M
Circadian Organization and Disorder in Alzheimer's DiseaseR01AG068577 · NIA · UNIVERSITY OF PENNSYLVANIA · PI ANAFI, RON C. · 2020 to 2024
$2.0M
NCI NIH HHS R01 CA227485NIA NIH HHS R01 AG068577
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

circadian disruptioncircadian rhythmcritical carecritical illnessgene correlation analysisICUintensive care unittranscription

Identifiers

PMID36045754
PMCPMC9420996
OpenAlexW4291378021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.