Evidence map›Paper›PMID 36045734›Full record

ArticleFrontiers in public health2022

Influence of circulating nesfatin-1, GSH and SOD on insulin secretion in the development of T2DM.

Kangkang Huang, Yunlai Liang, Kun Wang, Jiahui Wu, Huidan Luo, Bin Yi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Review
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  12. Article
  13. Journal of inflammation research · 2024
    Article
  14. Protective effects ofFrontiers in microbiology · 2024
    Article
  15. Article
  16. Oxidative Regulation of Vascular CaAntioxidants (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kangkang HuangDepartment of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, China.
Yunlai LiangDepartment of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, China.
Kun WangDepartment of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, China.
Jiahui WuDepartment of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, China.
Huidan LuoDepartment of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, China.
Bin YiDepartment of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, China.
Xiangya Hospital Central South University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: To evaluate the correlation of nesfatin-1, GSH and SOD levels with β-cell insulin secretion and their influence on insulin secretion in the development of type 2 diabetes mellitus (T2DM). Materials and methods: 75 patients with T2DM, 67 with prediabetes and 37 heathy participants were recruited in this study. Serum levels of nesfatin-1, GSH and SOD were quantified and statistically analyzed. Results: The levels of nesfatin-1, GSH and SOD in T2DM were significantly decreased ( Conclusion: Serum nesfatin-1, GSH and SOD are important factors involving insulin secretion in the development of T2DM, which may help provide new ideas for forthcoming investigations on the roles of these factors in pathogenesis of T2DM, as well as for active prediction and prevention of prediabetes before it develops into overt T2DM.

Indexed as

Diabetes Mellitus, Type 2Prediabetic StateGlutathioneHumansInsulin SecretionNucleobindinsSuperoxide DismutaseSuperoxide Dismutase-1GlutathioneNUCB2 protein, humanNucleobindinsSOD1 protein, humanSuperoxide DismutaseSuperoxide Dismutase-1GSHinsulin secretionprediabetesSODtype 2 diabetes mellitus

Identifiers

PMID36045734
PMCPMC9421132
OpenAlexW4291465191

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.