Evidence map›Paper›PMID 36045687›Full record

ArticleFrontiers in immunology2022

Comprehensive transcriptome profiling of urothelial cells following TNFα stimulation in an

Tadeja Kuret, Dominika Peskar, Mateja Erdani Kreft, Andreja Erman, Peter Veranič

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tadeja KuretInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Dominika PeskarInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Mateja Erdani KreftInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Andreja ErmanInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Peter VeraničInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
University of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urothelial cells of the urinary bladder play a critical role in the development and progression of interstitial cystitis/bladder pain syndrome (IC/BPS), a chronic and debilitating inflammatory disease. Given the lack of data on the exact phenotype and function of urothelial cells in an inflammatory setting (as in IC/BPS), we performed the first in-depth characterization of these cells using RNA sequencing, qPCR, ELISA, Western blot, and immunofluorescence. After TNFα stimulation, urothelial cells in the

Indexed as

Cystitis, InterstitialGene Expression ProfilingHumansTumor Necrosis Factor-alphaUrinary BladderTumor Necrosis Factor-alphabladder pain syndromeinflammationinterstitial cystitisproinflammatory cytokinesRNA sequencingtranscriptomicsurothelial cells

Identifiers

PMID36045687
PMCPMC9421144
OpenAlexW4291465259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.