Evidence map›Paper›PMID 36045651›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

The Effects of Probiotics Supplementation on Clinical Status and Biomarkers of Oxidative Damage and Inflammation in Children with Brucellosis: A Randomized, Double-Blind, and Placebo-Controlled Trial.

Noushin Zamani, Zeinab Ganjy, Mohammad Reza Sharif, Abbas Taghavi Ardakani, Davood Kheirkhah, Mansour Sayyah, Ali Azimi, Alireza Sharif

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Noushin ZamaniInfectious Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Zeinab GanjyInfectious Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Mohammad Reza SharifInfectious Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.ORCID https://orcid.org/0000-0002-2049-3370
Abbas Taghavi ArdakaniInfectious Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Davood KheirkhahDepartment of Pediatrics, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
Mansour SayyahInfectious Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Ali AzimiClinical Research Development Unit, Shahid Beheshti Hospital, Kashan University of Medical Sciences, Kashan, Iran.
Alireza SharifInfectious Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Kashan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Increased levels of inflammatory cytokines and oxidative damage may play crucial roles in the pathogenesis of brucellosis. The purpose of this trial was to evaluate the impact of probiotics administration on clinical status and biomarkers of oxidative damage and inflammation in pediatric patients diagnosed with brucellosis. Methods: This randomized, double-blind, and placebo-controlled trial was performed by recruiting 40 patients, 8-15 years of age, who had been diagnosed with brucellosis. Study participants were randomly allocated into two groups to receive either probiotics supplement or placebo ( Results: Following 8-week intervention, probiotics supplementation substantially improved total antioxidant capacity ( Conclusion: Overall, probiotics intake had beneficial impact on clinical status and body antioxidative defense system in pediatric patients with brucellosis.

Identifiers

PMID36045651
PMCPMC9423965
OpenAlexW4294126291

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.