Evidence map›Paper›PMID 36045438›Full record

ArticleMolecular nutrition & food research2022

Modification of Diet to Reduce the Stemness and Tumorigenicity of Murine and Human Intestinal Cells.

Stephanie May, Kirsty R Greenow, Adam T Higgins, Anna V Derrick, Elaine Taylor, Pan Pan, Maria Konstantinou, Colin Nixon, Thomas E Wooley, Owen J Sansom and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular nutrition & food research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Plants (Basel, Switzerland) · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Stephanie MayEuropean Cancer Stem Cell Research Institute, School of Biosciences, Cardiff University, Cardiff, CF24 4HQ, UK.
Kirsty R GreenowEuropean Cancer Stem Cell Research Institute, School of Biosciences, Cardiff University, Cardiff, CF24 4HQ, UK.
Adam T HigginsEuropean Cancer Stem Cell Research Institute, School of Biosciences, Cardiff University, Cardiff, CF24 4HQ, UK.
Anna V DerrickEuropean Cancer Stem Cell Research Institute, School of Biosciences, Cardiff University, Cardiff, CF24 4HQ, UK.
Elaine TaylorEuropean Cancer Stem Cell Research Institute, School of Biosciences, Cardiff University, Cardiff, CF24 4HQ, UK.
Pan PanDivision of Haematology and Oncology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53226, USA.
Maria KonstantinouEuropean Cancer Stem Cell Research Institute, School of Biosciences, Cardiff University, Cardiff, CF24 4HQ, UK.
Colin NixonCRUK Beatson Institute, Switchback Road, Bearsden, Glasgow, G61 1BD, UK.
Thomas E WooleySchool of Mathematics, Cardiff University, Senghennydd Road, Cardiff, CF24 4AG, UK.
Owen J SansomCRUK Beatson Institute, Switchback Road, Bearsden, Glasgow, G61 1BD, UK.
Li-Shu WangDivision of Haematology and Oncology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53226, USA.
Lee ParryEuropean Cancer Stem Cell Research Institute, School of Biosciences, Cardiff University, Cardiff, CF24 4HQ, UK.ORCID 0000-0002-4467-9196
Cardiff University · GBCancer Research UK Scotland Institute · GBMedical College of Wisconsin · USUniversity Hospital of Wales · GB

Funding

Cancer Research UK A17196Cancer Research UK C1295/A15937
6 · The paper itself

Abstract

scopeBlack raspberries (BRBs) have colorectal cancer (CRC) chemo-preventative effects. As CRC originates from an intestinal stem cell (ISC) this study has investigated the impact of BRBs on normal and mutant ISCs. METHODS AND

resultsMice with an inducible Apc

conclusionBRBs play a role in CRC chemoprevention by protectively regulating the ISC compartment and further supports the use of BRBs in CRC prevention.

Indexed as

RubusAnimalsColonDietHumansIntestinal MucosaIntestinesMiceStem Cellsanthocyaninsblack raspberrieschemopreventioncolorectal cancerintestinal stem cells

Identifiers

PMID36045438
PMCPMC9539894
OpenAlexW4293919809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.