Evidence map›Paper›PMID 36045267›Full record

ArticleHeart and vessels2023

Drug-coated balloons versus drug-eluting stents for coronary de novo lesions in dialysis patients.

Naohiro Funayama, Shingo Muratsubaki, Ryuta Ito, Toshiyuki Tobisawa, Takao Konishi

Open access · hybridAbstract read
In one paragraph

Article in Heart and vessels, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Application of Drug-Coated Balloons in Complex High Risk and Indicated Percutaneous Coronary Interventions.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Review
  6. Observational
  7. Article
  8. Management of Stent Underexpansion and Aorto-ostial Lesions.Interventional cardiology (London, England) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Naohiro FunayamaDivision of Cardiovascular Medicine, Hokkaido Cardiovascular Hospital, West 13, South 27, Chuou-ku, Sapporo, Hokkaido, 064-8622, Japan. funa_nao@hotmail.com.
Shingo MuratsubakiDivision of Cardiovascular Medicine, Hakodate Goryoukaku Hospital, 38-3, Goryoukaku-cho, Hakodate, Hokkaido, 040-8611, Japan.
Ryuta ItoDivision of Cardiovascular Medicine, Nagoya Kyoritsu Hospital, 1-172, Hokke, Nakagawa-ku, Nagoya, Aichi, 454-0933, Japan.
Toshiyuki TobisawaDivision of Cardiovascular Medicine, Asahikawa Red Cross Hospital, 1-1, Akebono, Asahikawa, Hokkaido, 070-8530, Japan.
Takao KonishiDivision of Cardiovascular Medicine, Hokkaido University Hospital, West 5, North 14, Kita-ku, Sapporo, Hokkaido, 060-8648, Japan.
Cardiovascular Center Hokkaido Ohno Hospital · JPHakodate National Hospital · JPHokkaido University Hospital · JPJapanese Red Cross Asahikawa Hospital · JPNagoya Kyouritsu Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to compare the efficacy of drug-coated balloon (DCB) angioplasty with drug-eluting stent (DES) angioplasty in the treatment of de novo coronary artery lesions in dialysis patients.

methodWe retrospectively enrolled 400 consecutive dialysis patients with 464 coronary de novo lesions treated by DCB or DES from five participating institutions in Japan. The primary endpoint was target lesion revascularization (TLR) at 12 months. We performed serial coronary angiographic analysis.

resultsThere were no significant differences in the rate of TLR between the groups in either crude or propensity score-matched analysis (DES 14.1% vs. DCB 14.7%, P = 0.864, DES 12.1% vs. 12.1%, P = 1.00). Target lesion thrombosis was not observed in the DCB group; however, stent thrombosis was observed in 7 patients (2.2%) in the DES group. The rate of binary restenosis was similar in both groups (DES, 20.9% vs. DCB, 22.8%; P = 0.749). The late lumen loss at follow-up was significantly greater in the DES group than in the DCB group (0.61 ± 0.76 mm vs 0.22 ± 0.48 mm; P < 0.001). Late lumen enlargement was observed in 38.6% of patients in the DCB group.

conclusionThe efficacy of DCB angioplasty for de novo coronary artery lesions in dialysis patients was similar to that of DES angioplasty in the real world. Drug-coated balloon angioplasty can be an acceptable treatment for de novo coronary artery lesions in dialysis patients.

Indexed as

Angioplasty, Balloon, CoronaryCoronary Artery DiseaseCoronary RestenosisDrug-Eluting StentsCoated Materials, BiocompatibleCoronary AngiographyHumansRenal DialysisRetrospective StudiesStentsTreatment OutcomeCoated Materials, BiocompatibleDe novo lesionDialysis patientDrug-coated balloonDrug-eluting stent

Identifiers

PMID36045267
PMCPMC9898424
OpenAlexW4293919586

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.