Evidence map›Paper›PMID 36045139›Full record

ArticleScientific reports2022

A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function.

Rachid Boutoual, Hyunsun Jo, Indra Heckenbach, Ritesh Tiwari, Herbert Kasler, Chad A Lerner, Samah Shah, Birgit Schilling, Vincenzo Calvanese, Matthew J Rardin and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. tRNAs at the Virus-Host Interface.Wiley interdisciplinary reviews. RNA
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Rachid BoutoualBuck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA. RBoutoual@buckinstitute.org.
Hyunsun JoGladstone Institutes and University of California, San Francisco, San Francisco, CA, 94158, USA.
Indra HeckenbachBuck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA.
Ritesh TiwariBuck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA.
Herbert KaslerBuck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA.
Chad A LernerBuck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA.
Samah ShahBuck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA.
Birgit Schilling
Vincenzo CalvaneseGladstone Institutes and University of California, San Francisco, San Francisco, CA, 94158, USA.
Matthew J RardinAmgen Research, Amgen Inc., South San Francisco, CA, 94080, USA.
Morten Scheibye-KnudsenCenter for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
Eric VerdinBuck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA, 94945, USA. EVerdin@buckinstitute.org.
Buck Institute for Research on Aging · USGladstone Institutes · USAmgen (United States) · USUniversity of California, San Francisco · USUniversity of Copenhagen · DK

Funding

TripleTOF 5600 High Resolution Mass SpectrometerS10OD016281 · OD · BUCK INSTITUTE FOR RESEARCH ON AGING · PI GIBSON, BRADFORD WAYNE · 2013 to 2013
$597k
NIH HHS S10 OD016281
6 · The paper itself

Abstract

Post-translational modifications, such as lysine acetylation, regulate the activity of diverse proteins across many cellular compartments. Protein deacetylation in mitochondria is catalyzed by the enzymatic activity of the NAD

Indexed as

Histone AcetyltransferasesRNA Processing, Post-TranscriptionalAnimalsMammalsMitochondrial ProteinsProtein BiosynthesisRNA, MitochondrialRNA, TransferHistone AcetyltransferasesMitochondrial ProteinsRNA, MitochondrialRNA, Transfer

Identifiers

PMID36045139
PMCPMC9433433
OpenAlexW4293764695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.