Evidence map›Paper›PMID 36045128›Full record

ArticleNature communications2022

Structural basis of ion uptake in copper-transporting P

Nina Salustros, Christina Grønberg, Nisansala S Abeyrathna, Pin Lyu, Fredrik Orädd, Kaituo Wang, Magnus Andersson, Gabriele Meloni, Pontus Gourdon

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A broad-spectrum inhibitor of copper-exporting PProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. The role of metal ions iron, copper, and zinc in the immune microenvironment of gastric cancer.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  6. A First-In-Class Broad Spectrum Inhibitor of Copper Exporting PbioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. The structure and function of P5A-ATPases.Nature communications · 2024
    Article
  17. In vitro reconstitution of transition metal transporters.The Journal of biological chemistry · 2024
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Nina SalustrosDepartment of Biomedical Sciences, Copenhagen University, Maersk Tower 7-9, Nørre Allé 14, DK-2200, Copenhagen, Denmark.ORCID 0000-0002-3504-5917
Christina GrønbergDepartment of Biomedical Sciences, Copenhagen University, Maersk Tower 7-9, Nørre Allé 14, DK-2200, Copenhagen, Denmark.
Nisansala S AbeyrathnaDepartment of Chemistry and Biochemistry, The University of Texas at Dallas, 800W Campbell Rd., Richardson, TX, 75080, USA.
Pin LyuDepartment of Biomedical Sciences, Copenhagen University, Maersk Tower 7-9, Nørre Allé 14, DK-2200, Copenhagen, Denmark.
Fredrik OräddDepartment of Chemistry, Umeå University, Linneaus Väg 10, SE-901 87, Umeå, Sweden.
Kaituo WangDepartment of Biomedical Sciences, Copenhagen University, Maersk Tower 7-9, Nørre Allé 14, DK-2200, Copenhagen, Denmark.ORCID 0000-0002-5922-7109
Magnus AnderssonDepartment of Chemistry, Umeå University, Linneaus Väg 10, SE-901 87, Umeå, Sweden.ORCID 0000-0002-3364-6647
Gabriele MeloniDepartment of Chemistry and Biochemistry, The University of Texas at Dallas, 800W Campbell Rd., Richardson, TX, 75080, USA.ORCID 0000-0003-4976-1401
Pontus GourdonDepartment of Biomedical Sciences, Copenhagen University, Maersk Tower 7-9, Nørre Allé 14, DK-2200, Copenhagen, Denmark. pontus@sund.ku.dk.ORCID 0000-0002-8631-3539
Maersk (Denmark) · DKThe University of Texas at Dallas · USUmeå University · SEUniversity of Copenhagen · DK

Funding

Principles of selectivity and translocation in transition metal transporters, metallochaperones, and associated metalloproteinsR35GM128704 · NIGMS · UNIVERSITY OF TEXAS DALLAS · PI Gabriele Meloni · 2018 to 2026
$3.5M
NIGMS NIH HHS R35 GM128704
6 · The paper itself

Abstract

Copper is essential for living cells, yet toxic at elevated concentrations. Class 1B P-type (P

Indexed as

CopperCopper-Transporting ATPasesAdenosine TriphosphatasesBiological TransportHumansMolecular ChaperonesAdenosine TriphosphatasesCopperCopper-Transporting ATPasesMolecular Chaperones

Identifiers

PMID36045128
PMCPMC9433437
OpenAlexW4293764537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.