Evidence map›Paper›PMID 36044916›Full record

SynthesisRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2022

The Effect of Neuromodulatory Drugs on the Intensity of Chronic Pelvic Pain in Women: A Systematic Review.

Marcela Almeida Andrade, Leila Cristina Soares, Marco Aurélio Pinho de Oliveira

Open access · diamondAbstract readSystematic Review
In one paragraph

Synthesis in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Beyond nociception: rethinking pain in ovarian endometriosis a pilot study.Frontiers in pain research (Lausanne, Switzerland) · 2026
    Article
  4. Clinical Guidance Paper VVOG: Pharmacological treatment of endometriosis-related pain.European journal of obstetrics & gynecology and reproductive biology: X · 2025
    Article
  5. Review
  6. Evaluation and Medical Management of Chronic Pelvic Pain.Seminars in interventional radiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marcela Almeida AndradeUniversidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID 0000-0001-7208-9321
Leila Cristina SoaresUniversidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID 0000-0001-8360-3189
Marco Aurélio Pinho de OliveiraUniversidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID 0000-0002-4645-1638
Universidade do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effect of neuromodulatory drugs on the intensity of chronic pelvic pain (CPP) in women. DATA SOURCES: Searches were carried out in the PubMed, Cochrane Central, Embase, Lilacs, OpenGrey, and Clinical Trials databases. SELECTION OF STUDIES: The searches were carried out by two of the authors, not delimiting publication date or original language. The following descriptors were used: DATA COLLECTION: The following data were extracted: author, year of publication, setting, type of study, sample size, intervention details, follow-up time, and results. DATA SYNTHESIS: A total of 218 articles were found, with 79 being excluded because they were repeated, leaving 139 articles for analysis: 90 were excluded in the analysis of the titles, 37 after reading the abstract, and 4 after reading the articles in full, and 1 could not be found, therefore, leaving 7 articles that were included in the review.

conclusionMost of the studies analyzed have shown pain improvement with the help of neuromodulators for chronic pain. However, no improvement was found in the study with the highest statistical power. There is still not enough evidence that neuromodulatory drugs reduce the intensity of pain in women with CPP.

Indexed as

Chronic PainCitalopramAmitriptylineAnticonvulsantsAntidepressive AgentsAntidepressive Agents, TricyclicDuloxetine HydrochlorideFemaleGabapentinHumansImipramineNorepinephrineNortriptylinePelvic PainPregabalinSerotoninAmitriptylineAnticonvulsantsAntidepressive AgentsAntidepressive Agents, TricyclicCitalopramDuloxetine HydrochlorideGabapentinImipramineNorepinephrineNortriptylinePregabalinSerotoninSertralineVenlafaxine Hydrochloride

Identifiers

PMID36044916
PMCPMC9948135
OpenAlexW4294124348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.