Evidence map›Paper›PMID 36044529›Full record

ArticlePloS one2022

Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania.

Kady D Waggle, Marissa P Griffith, Lei Zhu, Vaughn S Cooper, Daniel J Snyder, Vatsala Srinivasa, Tung Phan, Alan Wells, Graham M Snyder, Daria Van Tyne and 2 more

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kady D WaggleMicrobial Genomics Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Marissa P GriffithMicrobial Genomics Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Lei ZhuMicrobial Genomics Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Vaughn S CooperDepartment of Microbiology and Molecular Genetics and Center for Evolutionary Biology and Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.ORCID 0000-0001-7726-0765
Daniel J SnyderMicrobial Genome Sequencing Center, LLC, Pittsburgh, Pennsylvania, United States of America.
Vatsala SrinivasaMicrobial Genomics Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Tung PhanDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Alan WellsDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Graham M SnyderDepartment of Infection Control and Hospital Epidemiology, UPMC Presbyterian, Pittsburgh, Pennsylvania, United States of America.ORCID 0000-0001-5562-8880
Daria Van TyneDivision of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
Lee H HarrisonMicrobial Genomics Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Jane W MarshMicrobial Genomics Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.ORCID 0000-0001-8271-651X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses of SARS-CoV-2 to vaccination.

Indexed as

COVID-19Viral VaccinesAntibodies, ViralGenomicsHumansPennsylvaniaSARS-CoV-2Antibodies, ViralViral Vaccines

Identifiers

PMID36044529
PMCPMC9432771

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.