ArticleActa bio-medica : Atenei Parmensis2022
The treatment of knee cartilage lesions: state of the art.
Article in Acta bio-medica : Atenei Parmensis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Effectiveness of platelet-rich plasma plus microfracture compared with microfracture alone in the treatment of knee cartilage lesions: a systematic review and meta-analysis of comparative studies.International journal of surgery (London, England) · 2026Article
- LIPO-AMIC Technique Description: Autologous Matrix Induced-Chondrogenesis With Microfragmented Adipose Tissue Graft.Arthroscopy techniques · 2025Article
- Cemented vs. Cementless Fixation in Primary Knee Replacement: A Narrative Review.Materials (Basel, Switzerland) · 2024Review
- Hyalofast Cartilage Repair Surgery with a Full Load-Bearing Rehabilitation Program One Day after Operation Reduces the Time for Professional Athletes to Return to Play.Medicina (Kaunas, Lithuania) · 2023Article
- Platelet rich plasma combined with arthroscopic microfracture versus arthroscopic microfracture alone for the treatment of knee cartilage injury.American journal of translational research · 2023Article
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Authors and funding
7 authors.
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Abstract
The management and repair of knee cartilage lesions currently represents a challenge for the orthopaedic surgeon. Identifiable causes are the characteristics of the involved tissues themselves and the presence of poor vascularization, which is responsible for overall reduced repair capacity. The literature reports three types of cartilage lesions' treatment modalities: chondroprotection, chondroreparation and chondrogeneration. The preference for one or the other therapeutic option depends on the pattern of the lesion and the clinical conditions of the patient. Each treatment technique is distinguished by the quality of the restorative tissue that is generated. In particular, the chondrorigeneration represents the last frontier of regenerative medicine, as it aims at the complete restoration of natural cartilage. However, the most recent literature documents good results only in the short and medium terms. In recent years the optimization of chondroregeneration outcomes is based on the modification of the scaffolds and the search for new chondrocyte sources, in order to guarantee satisfactory long-term results.
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