Evidence map›Paper›PMID 36043958›Full record

ReviewActa bio-medica : Atenei Parmensis2022

A Short Review on Growth and Endocrine Long-term Complications in Children and Adolescents with β-Thalassemia Major: Conventional Treatment versus Hematopoietic Stem Cell Transplantation.

Shayma Ahmed, Ashraf Soliman, Vincenzo De Sanctis, Nada Alaaraj, Fawzia Alyafei, Noor Hamed, Mohamed Yassin

Open access · greenAbstract readReview
In one paragraph

Review in Acta bio-medica : Atenei Parmensis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Association ofMolecular genetics and metabolism reports · 2024
    Article
  8. Review
  9. A Particular Focus on the Prevalence ofInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Shayma AhmedDepartment of Pediatrics, Hamad General Hospital, Doha, Qatar. SMohammed5@hamad.qa.
Ashraf Soliman. atsoliman56@gmail.com.
Vincenzo De SanctisPediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara, Italy. vdesanctis@libero.it.
Nada AlaarajDepartment of Pediatrics, Hamad General Hospital, Doha, Qatar. nadaalaaraj@gmail.com.
Fawzia AlyafeiDepartment of Pediatrics, Hamad General Hospital, Doha, Qatar. fawzia2005@yahoo.com.
Noor HamedDepartment of Pediatrics, Hamad General Hospital, Doha, Qatar. NHamed@hamad.qa.
Mohamed YassinDepartment of Hematology and Oncology, National Centre for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar. yassinmoha@gmail.com.
Hamad General Hospital · QANational Center for Cancer Care and Research · QAUniversity of the Philippines Diliman · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The conventional treatment of β-thalassemia (β-TM) patients is based on the correction of anemia through regular blood transfusions and iron chelation therapy. However, allogeneic hematopoietic stem cell transplantation (HSCT) remains the only currently available technique that has curative potential. Variable frequency and severity of long-term growth and endocrine changes after conventional treatment as well as after HSCT have been reported by different centers. The goal of this mini-review is to summarize and update knowledge about long-term growth and endocrine changes after HSCT in patients with β-TM in comparison to those occurring in β-TM patients on conventional treatment. Regular surveillance, early diagnosis, treatment, and follow-up in a multi-disciplinary specialized setting are suggested to optimize the patient's quality of life (www.actabiomedica.it).

Indexed as

beta-ThalassemiaHematopoietic Stem Cell TransplantationAdolescentBlood TransfusionChelation TherapyChildHumansQuality of Life

Identifiers

PMID36043958
PMCPMC9534255
OpenAlexW4293900714

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.