Evidence map›Paper›PMID 36043874›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2022

How I Approach Leishmaniasis: Diagnosis and Treatment in the United States.

Tara E Ness, Rachel Martin-Blais, Jill E Weatherhead

Open access · greenAbstract read
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. CutaneousJAAD case reports · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tara E NessDivision of Pediatric Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-4425-418X
Rachel Martin-BlaisDivision of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-5546-1072
Jill E WeatherheadDivision of Pediatric Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
Baylor College of Medicine · USChildren's Hospital of Philadelphia · US

Funding

Discovering the Immunologic Mechanism of Ascaris-induced Allergic Airway Disease.K08AI143968 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI WEATHERHEAD, JILL ELIZABETH · 2020 to 2024
$911k
National Institute of Allergy and Infectious DiseasesNIAID NIH HHS K08 AI143968NIAID NIH HHS L40 AI147233NIH HHS
6 · The paper itself

Abstract

Leishmaniasis is a vector-borne disease caused by over 20 species of obligate intracellular protozoa belonging to the genus Leishmania. Leishmaniasis has a global distribution, including in the United States, and can cause a spectrum of clinical syndromes, including cutaneous, mucosal, and visceral diseases depending on host factors and the infecting Leishmania spp. Accurate diagnosis, including Leishmania species identification, is an important step to guide the most appropriate therapeutic intervention. Antileishmanial therapy is dependent on the Leishmania spp. identified, the clinical syndrome, and the child's immune system. However, many treatment regimens for children have been extrapolated from adult clinical trials, which may lead to underdosing and subsequent poor outcomes in infected children. Additional research is urgently needed to help guide therapy for children and determine appropriate antileishmanial agents, doses, and treatment courses for children with leishmaniasis.

Indexed as

Antiprotozoal AgentsLeishmaniaLeishmaniasisLeishmaniasis, CutaneousChildHumansSkinUnited StatesAntiprotozoal Agentsleishmaniasisneglected tropical diseaseparasitestropical medicine

Identifiers

PMID36043874
PMCPMC9720369
OpenAlexW4293762776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.