Evidence map›Paper›PMID 36043477›Full record

ArticleThe British journal of radiology2022

Right-to-left ventricle ratio determined by machine learning algorithms on CT pulmonary angiography images predicts prolonged ICU length of stay in operated chronic thromboembolic pulmonary hypertension.

Sumer Shikhare, Indranil Balki, Yuliang Shi, John Kavanagh, Laura Donahoe, Wei Xu, Dmitry Rozenberg, Marc de Perrot, Micheal McInnis

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sumer ShikhareDivision of Cardiothoracic Imaging, Joint Department of Medical Imaging, University of Toronto, Toronto, Canada.
Indranil BalkiDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.
Yuliang ShiDepartment of Biostatistics, Princess Margaret Cancer Center, Toronto, Canada.
John KavanaghDivision of Cardiothoracic Imaging, Joint Department of Medical Imaging, University of Toronto, Toronto, Canada.
Laura DonahoeDivision of Thoracic Surgery, Department of Surgery, University of Toronto, Toronto General Hospital, Toronto, Canada.
Wei Xu7Department of Biostatistics, Princess Margaret Cancer Center, Toronto, Canada.
Dmitry RozenbergDivision of Respirology, Department of Medicine, University of Toronto, Toronto General Hospital, Toronto, Canada.
Marc de PerrotDivision of Thoracic Surgery, Department of Surgery, University of Toronto, Toronto General Hospital, Toronto, Canada.
Micheal McInnisDivision of Cardiothoracic Imaging, Joint Department of Medical Imaging, University of Toronto, Toronto, Canada.
University of Toronto · CAPrincess Margaret Cancer Centre · CAToronto General Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRight-to-left ventricle diameter ratio (dRV/dLV) on CT pulmonary angiography (CTPA) is a predictor of outcomes in non-operated chronic thromboembolic pulmonary hypertension (CTEPH) patients. The purpose of this study is to evaluate the performance of a novel machine learning (ML) algorithm for dRV/dLV measurement in operated CTEPH patients and its association with post-operative outcomes.

methodsThis retrospective study reviewed consecutive CTEPH patients who underwent pulmonary endarterectomy between 2013 and 2017. ML calculated dRV/dLV on pre-operative CTPA and compared with manual measures. Associations of dRV/dLV with patient characteristics and post-operative outcomes were evaluated including intensive care (ICU) and hospital length of stay (LOS) using multivariable linear regression analysis. Prolonged LOS was defined as greater than median.

resultsML segmented the ventricles in 99/125 (79%) patients. The most common cause of failure was misidentification of the moderator band as the interventricular septum (7.9%). Mean dRV/dLV by ML was 1.4 ± 0.4 and strongly correlated with manual measures (

conclusiondRV/dLV was associated with CTEPH severity and independently associated with prolonged ICU LOS. This CT parameter may therefore assist in perioperative planning. Further refinement of the ML algorithm or CTPA technique is required to avoid errors in ventricular segmentation. ADVANCES IN KNOWLEDGE: Automated right-to-left ventricle ratio measurement by machine learning is feasible and is independently associated with outcome after pulmonary endarterectomy.

Indexed as

Hypertension, PulmonaryPulmonary EmbolismAngiographyChronic DiseaseComputed Tomography AngiographyHeart VentriclesHumansIntensive Care UnitsLength of StayMachine LearningRetrospective Studies

Identifiers

PMID36043477
PMCPMC9793468
OpenAlexW4293764510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.