ReviewJournal of diabetes2022
Alterations in epidermal function in type 2 diabetes: Implications for the management of this disease.
Review in Journal of diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- Superficial Fungal Infection Associations with Comorbid Diseases and Risk Factors: An Analysis of Global Burden of Disease 2023.Infectious disease reports · 2026Article
- A Flexible Wearable Glucose Sensor for Noninvasive Diabetes Screening: Functional Equivalence and Model Interpretability.Biosensors · 2026Article
- Analysis of correlated factors of skin pruritus in type 2 diabetes mellitus.BMC endocrine disorders · 2026Observational
- Beyond clinical closure: functional skin barrier recovery to prevent diabetic foot ulcer recurrence: a narrative review.Frontiers in endocrinology · 2026Review
- Hemorrhoid risk among people with diabetes mellitus using glucose lowering agents.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Umbelliferone preserves skin epidermal barrier integrity in diabetes-induced keratinocytes by regulating actin dynamics and suppressing ROS-mediated apoptosis.Nutrition & diabetes · 2025Article
- Skin manifestations in diabetes-what is new?Frontiers in medicine · 2025Review
- Skin Care Supports Overall Well-Being.Clinical, cosmetic and investigational dermatology · 2025Article
- Effect of changes in skin properties due to diabetes mellitus on the titration period of transdermal fentanyl: single-center retrospective study and diabetic animal model study.Journal of pharmaceutical health care and sciences · 2024Article
- Stratum corneum hydration levels are negatively correlated with HbA1c levels in the elderly Chinese.Journal of diabetes · 2024Article
- Amputation Triggers Long-Range Epidermal Permeability Changes in Evolutionarily Distant Regenerative Organisms.bioRxiv : the preprint server for biology · 2024Article
- Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection.Cell reports · 2024Article
- Evaluation of Morphological and Structural Skin Alterations on Diabetic Subjects by Biophysical and Imaging Techniques.Life (Basel, Switzerland) · 2023Article
- Body Mass Index z Scores Correlate with Epidermal Function in Chinese Children.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Improvement in Cutaneous Conditions Can Benefit Some Health Conditions in the Elderly.Clinical interventions in aging · 2023Article
- Alterations in epidermal function in type 2 diabetes: Implications for the management of this disease.Journal of diabetes · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
Epidermal function is regulated by numerous exogenous and endogenous factors, including age, psychological stress, certain skin disorders, ultraviolet irradiation and pollution, and epidermal function itself can regulate cutaneous and extracutaneous functions. The biophysical properties of the stratum corneum reflect the status of both epidermal function and systemic conditions. Type 2 diabetes in both murine models and humans displays alterations in epidermal functions, including reduced levels of stratum corneum hydration and increased epidermal permeability as well as delayed permeability barrier recovery, which can all provoke and exacerbate cutaneous inflammation. Because inflammation plays a pathogenic role in type 2 diabetes, a therapy that improves epidermal functions could be an alternative approach to mitigating type 2 diabetes and its associated cutaneous disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.