Evidence map›Paper›PMID 36043138›Full record

ArticleBrain communications2022

Brain atrophy in middle age using magnetic resonance imaging scans from Japan's health screening programme.

Susumu Mori, Kengo Onda, Shohei Fujita, Toshiaki Suzuki, Mikimasa Ikeda, Khin Zay Yar Myint, Jun Hikage, Osamu Abe, Hidekazu Tomimoto, Kenichi Oishi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  3. Dyslipidemia and cerebral atrophy among health check-up individuals: A cross-sectional study.International journal of cardiology. Cardiovascular risk and prevention · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Susumu MoriDepartment of Radiology, Johns Hopkins University, School of Medicine, 330 Traylor Bldg, 217 Rutland Ave, Baltimore, MD 21205, USA.ORCID https://orcid.org/0000-0002-1180-2629
Kengo OndaTokyo Medical and Dental University, 1 Chome-5-45 Yushima, Bunkyo City, Tokyo 113-0034, Japan.
Shohei FujitaDepartment of Radiology, The University of Tokyo, Graduate School of Medicine, 7-3-1 Hongo, Bunkyo City, Tokyo 113-0033, Japan.ORCID https://orcid.org/0000-0003-4276-6226
Toshiaki SuzukiResorttrust.Inc, Engyou Bldg.8F, Roppongi 7-15-14, Minato-ku, Tokyo 106-0032, Japan.
Mikimasa IkedaResorttrust.Inc, Engyou Bldg.8F, Roppongi 7-15-14, Minato-ku, Tokyo 106-0032, Japan.
Khin Zay Yar MyintAdvanced Medical Care Inc., Midtown Tower 6F, Akasaka 9-7-1, Minato-ku, Tokyo 107-6206, Japan.
Jun HikageResorttrust.Inc, Engyou Bldg.8F, Roppongi 7-15-14, Minato-ku, Tokyo 106-0032, Japan.
Osamu AbeDepartment of Radiology, The University of Tokyo, Graduate School of Medicine, 7-3-1 Hongo, Bunkyo City, Tokyo 113-0033, Japan.
Hidekazu TomimotoDepartment of Neurology, Hidekazu Tomimoto, Mie University 2-174, Edobashi, Tsu, Mie 514-0001, Japan.
Kenichi OishiDepartment of Radiology, Johns Hopkins University, School of Medicine, 330 Traylor Bldg, 217 Rutland Ave, Baltimore, MD 21205, USA.
Junichi TaguchiTokyo Midtown Clinic, 9-7-1-6F Akasaka, Minato, Tokyo 107-6206, Japan.
Johns Hopkins University · USThe University of Tokyo · JPMie University · JPTokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although health screening plays a key role in the management of chronic diseases associated with lifestyle choices, brain health is not generally monitored, remaining a black box prior to the manifestation of clinical symptoms. Japan is unique in this regard, as brain MRI scans have been widely performed for more than two decades as part of Brain Dock, a comprehensive health screening programme. A vast number of stored images (well over a million) of longitudinal scans and extensive health data are available, offering a valuable resource for investigating the prevalence of various types of brain-related health conditions occurring throughout adulthood. In this paper, we report on the findings of our preliminary quantitative analysis of T

Indexed as

atrophybraindementiamodifiableMRI

Identifiers

PMID36043138
PMCPMC9416065
OpenAlexW4292582806

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.