Evidence map›Paper›PMID 36043105›Full record

ArticleRSC advances2022

Anti-multiple myeloma potential of resynthesized belinostat derivatives: an experimental study on cytotoxic activity, drug combination, and docking studies.

Hong Phuong Nguyen, Quang De Tran, Cuong Quoc Nguyen, Tran Phuong Hoa, Tran Duy Binh, Huynh Nhu Thao, Bui Thi Buu Hue, Nguyen Trong Tuan, Quang Le Dang, Nguyen Quoc Chau Thanh and 3 more

Abstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hong Phuong NguyenDepartment of Biomedical Science, BK21 FOUR Program in Biomedical Science and Engineering, Inha University College of Medicine Incheon 22212 South Korea sugeun.yang@inha.ac.kr +82-32-890-1199 +82-32-890-2832.
Quang De TranDepartment of Chemistry, College of Natural Sciences, Can Tho University Can Tho 90000 Vietnam tqde@ctu.edu.vn +84934527817.ORCID https://orcid.org/0000-0002-5381-0686
Cuong Quoc NguyenDepartment of Chemistry, College of Natural Sciences, Can Tho University Can Tho 90000 Vietnam tqde@ctu.edu.vn +84934527817.ORCID https://orcid.org/0000-0002-5641-5040
Tran Phuong HoaDepartment of Biomedical Science, BK21 FOUR Program in Biomedical Science and Engineering, Inha University College of Medicine Incheon 22212 South Korea sugeun.yang@inha.ac.kr +82-32-890-1199 +82-32-890-2832.
Tran Duy BinhDepartment of Biomedical Science, BK21 FOUR Program in Biomedical Science and Engineering, Inha University College of Medicine Incheon 22212 South Korea sugeun.yang@inha.ac.kr +82-32-890-1199 +82-32-890-2832.ORCID https://orcid.org/0000-0003-1591-2611
Huynh Nhu ThaoDepartment of Chemistry, College of Natural Sciences, Can Tho University Can Tho 90000 Vietnam tqde@ctu.edu.vn +84934527817.
Bui Thi Buu HueDepartment of Chemistry, College of Natural Sciences, Can Tho University Can Tho 90000 Vietnam tqde@ctu.edu.vn +84934527817.
Nguyen Trong TuanDepartment of Chemistry, College of Natural Sciences, Can Tho University Can Tho 90000 Vietnam tqde@ctu.edu.vn +84934527817.
Quang Le DangInstitute for Tropical Technology, Vietnam Academy of Science and Technology Hanoi 10000 Vietnam.ORCID https://orcid.org/0000-0001-7203-8081
Nguyen Quoc Chau ThanhDepartment of Chemistry, College of Natural Sciences, Can Tho University Can Tho 90000 Vietnam tqde@ctu.edu.vn +84934527817.
Nguyen Van KyDepartment of Chemistry, College of Natural Sciences, Can Tho University Can Tho 90000 Vietnam tqde@ctu.edu.vn +84934527817.
Minh Quan PhamGraduate University of Science and Technology, Vietnam Academy of Science and Technology Hanoi 100000 Vietnam.
Su-Geun YangDepartment of Biomedical Science, BK21 FOUR Program in Biomedical Science and Engineering, Inha University College of Medicine Incheon 22212 South Korea sugeun.yang@inha.ac.kr +82-32-890-1199 +82-32-890-2832.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma is a deadly cancer that is a complex and multifactorial disease. In the present study, 12 belinostat derivatives (four resynthesized and eight new), HDAC inhibitors, were resynthesized

Identifiers

PMID36043105
PMCPMC9364358

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.