Evidence map›Paper›PMID 36043049›Full record

ArticleiScience2022

Applying the auxin-based degron system for the inducible, reversible and complete protein degradation in

Leonie Lehmayer, Lukas Bernauer, Anita Emmerstorfer-Augustin

Abstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Engineering small peptide secretion inFrontiers in bioengineering and biotechnology · 2026
    Article
  3. Auxin-Induced Degradation of Target Proteins in Pichia pastoris.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  4. Article
  5. Human Sterols Are Overproduced, Stored and Excreted in Yeasts.International journal of molecular sciences · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Leonie LehmayerInstitute of Molecular Biotechnology, Graz University of Technology, NAWI Graz, Petersgasse 14/II, 8010 Graz, Austria.
Lukas BernauerInstitute of Molecular Biotechnology, Graz University of Technology, NAWI Graz, Petersgasse 14/II, 8010 Graz, Austria.
Anita Emmerstorfer-AugustinInstitute of Molecular Biotechnology, Graz University of Technology, NAWI Graz, Petersgasse 14/II, 8010 Graz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The auxin-inducible degron (AID) system is a useful technique to rapidly deplete any protein of interest "on-demand." In this study, we successfully established the AID system for the "biotech" yeast

Indexed as

microbiologymolecular biology

Identifiers

PMID36043049
PMCPMC9420516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.