Evidence map›Paper›PMID 36043014›Full record

ReviewCureus2022

Hepatitis Virus C-associated Nephropathy: A Review and Update.

Elmukhtar Habas, Khalifa L Farfar, Nada Errayes, Ala M Habas, Mehdi Errayes, Gamal Alfitori, Amnna Rayani, Mohamed Elgara, Aisha H Al Adab, Abdulnaser Elzouki

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Renal Manifestations of Chronic Hepatitis C: A Review.Journal of clinical medicine · 2024
    Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 5 countries.

Elmukhtar HabasInternal Medicine, Hamad General Hospital, Doha, QAT.
Khalifa L FarfarInternal Medicine, Alwakra Hospital, Alwakra, QAT.
Nada ErrayesEpidemiology, University of Lincoln, Lincoln, GBR.
Ala M HabasInternal Medicine, Tripoli Medical Hospital, Tripoli, LBY.
Mehdi ErrayesInternal Medicine, Hamad General Hospital, Doha, QAT.
Gamal AlfitoriInternal Medicine, Hamad General Hospital, Doha, QAT.
Amnna RayaniHemat-Oncology Department, Pediatric Tripoli Hospital, Tripoli University, Tripoli, LBY.
Mohamed ElgaraInternal Medicine, Hamad General Hospital, Doha, QAT.
Aisha H Al AdabPulmonary Medicine, Hamad General Hospital, Doha, QAT.
Abdulnaser ElzoukiInternal Medicine, Hamad General Hospital, Doha, QAT.
Mubarak Al Kabeer Hospital · KWUniversity of Lincoln · GBLincoln University - Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) infection causes hepatic and extrahepatic organ involvement. Chronic kidney disease (CKD) is a prevalent non-communicable disorder, accounting for significant morbidity and mortality worldwide. Acute kidney injury and CKD are not uncommon sequels of acute or chronic HCV infection. The pathogenesis of HCV-associated kidney injuries is not well explored. Excess cryoglobulin production occurs in HCV infection. The cryoglobulin may initiate immune complex-mediated vasculitis, inducing vascular thrombosis and inflammation due to cryoglobulin deposits. Furthermore, direct damage to nephron parts also occurs in HCV patients. Other contributory causes such as hypertension, diabetes, and genetic polymorphism enhance the risk of kidney damage in HCV-infected individuals. Implementing CKD prevention, regular evaluation, and therapy may improve the HCV burden of kidney damage and its related outcomes. Therefore, in this review, we discuss and update the possible mechanism(s) of kidney injury pathogenesis with HCV infection. We searched for related published articles in EMBASE, Google Scholar, Google, PubMed, and Scopus. We used various texts and phrases, including hepatitis virus and kidney, HCV and CKD, kidney pathology in viral hepatitis, kidney transplantation in HCV-infected patients, kidney allograft survival in viral hepatitis patients, mechanism of kidney pathology in viral hepatitis, dialysis and viral hepatitis, HCV infection and kidney injuries, and viral hepatitis and CKD progression, etc. to identify relevant articles.

Indexed as

cryoglobulinemiaglomerulonephritisgnhcv-associated gnhcv kidney injury pathogenesishepatitis chvc-associated nephropathy

Identifiers

PMID36043014
PMCPMC9412079
OpenAlexW4288033876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.