ArticleWater research X2022
Microbial paracetamol degradation involves a high diversity of novel amidase enzyme candidates.
Article in Water research X, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 58 citations in OpenAlex.
- Draft genome sequence of soil isolateMicrobiology resource announcements · 2026Article
- Enzyme association for environmental biotransformation reactions through contrastive learning of reaction center-specific fingerprints.Bioinformatics (Oxford, England) · 2026Article
- Advanced microbial engineering approaches for biodegradation of pharmaceutical pollutants.Biodegradation · 2025Review
- Biodegradation of Emerging Contaminants Controlled by Biological and Chemical Factors.Microorganisms · 2025Review
- First Insight into the Natural Attenuation of Emerging Contaminants Using a Metagenomics Approach from Drinking Water Sources in the Free State.Microorganisms · 2025Article
- Pseudomonas sp. MSW2-Mediated Biodegradation of Pharmaceutical Micropollutants: Experimental and In Silico Investigations.Current microbiology · 2025Article
- Biodegradation of paracetamol by Amycolatopsis sp. Poz 14.BMC research notes · 2025Article
- Impact of Tetracycline Stress on Water Quality and Rhizosphere Microbial Communities ofMicroorganisms · 2025Article
- Article
- Machine Learning Reveals Signatures of Promiscuous Microbial Amidases for Micropollutant Biotransformations.ACS environmental Au · 2025Article
- Microbes as Resources to Remove PPCPs and Improve Water Quality.Microbial biotechnology · 2025Review
- Delineating acetaminophen biodegradation kinetics and metabolomics using bacterial community.Biodegradation · 2024Article
- Hydroquinone Ecotoxicity: Unveiling Risks in Soil and River Ecosystems with Insights into Microbial Resilience.Toxics · 2024Article
- Bacteria use a catabolic patchwork pathway of apparently recent origin for degradation of the synthetic buffer compound TRIS.The ISME journal · 2024Article
- Pollutant profile complexity governs wastewater removal of recalcitrant pharmaceuticals.The ISME journal · 2024Article
- Microbial degradation of contaminants of emerging concern: metabolic, genetic and omics insights for enhanced bioremediation.Frontiers in bioengineering and biotechnology · 2024Review
- Acetaminophen-traces bioremediation with novel phenotypically and genotypically characterized 2 Streptomyces strains using chemo-informatics, in vivo, and in vitro experiments for cytotoxicity and biological activity.Journal, genetic engineering & biotechnology · 2023Article
- Analyzing microbial communities and their biodegradation of multiple pharmaceuticals in membrane bioreactors.Applied microbiology and biotechnology · 2023Article
- Transcriptomic Analysis of Acetaminophen Biodegradation byJournal of fungi (Basel, Switzerland) · 2023Article
- Diclofenac, ibuprofen, and paracetamol biodegradation: overconsumed non-steroidal anti-inflammatories drugs at COVID-19 pandemic.Frontiers in microbiology · 2023Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pharmaceuticals are relatively new to nature and often not completely removed in wastewater treatment plants (WWTPs). Consequently, these micropollutants end up in water bodies all around the world posing a great environmental risk. One exception to this recalcitrant conversion is paracetamol, whose full degradation has been linked to several microorganisms. However, the genes and corresponding proteins involved in microbial paracetamol degradation are still elusive. In order to improve our knowledge of the microbial paracetamol degradation pathway, we inoculated a bioreactor with sludge of a hospital WWTP (Pharmafilter, Delft, NL) and fed it with paracetamol as the sole carbon source. Paracetamol was fully degraded without any lag phase and the enriched microbial community was investigated by metagenomic and metatranscriptomic analyses, which demonstrated that the microbial community was very diverse. Dilution and plating on paracetamol-amended agar plates yielded two
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.