How much BiGAN and CycleGAN-learned hidden features are effective for COVID-19 detection from CT images? A comparative study.

Bidirectional generative adversarial networks (BiGANs) and cycle generative adversarial networks (CycleGANs) are two emerging machine learning models that, up to now, have been used as generative models, i.e., to generate output data sampled from a target probability distribution. However, these models are also equipped with encoding modules, which, after weakly supervised training, could be, in principle, exploited for the extraction of hidden features from the input data. At the present time, how these extracted features could be effectively exploited for classification tasks is still an unexplored field. Hence, motivated by this consideration, in this paper, we develop and numerically test the performance of a novel inference engine that relies on the exploitation of BiGAN and CycleGAN-learned hidden features for the detection of COVID-19 disease from other lung diseases in computer tomography (CT) scans. In this respect, the main contributions of the paper are twofold. First, we develop a kernel density estimation (KDE)-based inference method, which, in the training phase, leverages the hidden features extracted by BiGANs and CycleGANs for estimating the (