Evidence map›Paper›PMID 36042712›Full record

ArticleJournal of asthma and allergy2022

A Comparison of the Effectiveness of Asthma Medications on Asthma Exacerbations in Real World National Cohort.

Hye Jung Park, Soyoung Jeon, Hye Sun Lee, Bo Yeon Kim, Yu Jin Chae, Gui Ok Kim, Jung-Won Park, Jae-Hyun Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of asthma and allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hye Jung ParkDepartment of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-1862-1003
Soyoung JeonBiostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-9916-1917
Hye Sun LeeBiostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0001-6328-6948
Bo Yeon KimHealthcare Insurance Review & Assessment Service, Wonju, Republic of Korea.
Yu Jin ChaeHealthcare Insurance Review & Assessment Service, Wonju, Republic of Korea.
Gui Ok KimHealthcare Insurance Review & Assessment Service, Wonju, Republic of Korea.
Jung-Won ParkDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jae-Hyun LeeDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-0760-0071
Yonsei University · KRHealth Insurance Review and Assessment Service · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although a wide variety of asthma medications have been developed and are used in clinical practice, there is limited evidence of their comparative effects on asthma exacerbations. Methods: We used claims data provided by the Health Insurance Review and Assessment Service. We selected subjects commencing asthma treatment between July 1, 2017 and June 30, 2018, with no change in drug regimen. The primary outcome was asthma exacerbation requiring systemic corticosteroids. Cox regression analysis was used to assess outcomes considering the exacerbation-free period. Results: Of the 254,951 asthma subjects, 107,694 subjects (42.2%) experienced asthma exacerbation. Inhaled corticosteroids (ICSs) (hazard ratio [HR], 0.378-0.508), ICS-long-acting Conclusion: This real-world study showed that the effectiveness of asthma medications varied according to drug type, active ingredient, combination, and period of use, although effectiveness was significant in all cases studied.

Indexed as

asthmacombinationdrugexacerbationmedicationreal-world data

Identifiers

PMID36042712
PMCPMC9420439
OpenAlexW4292877244

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.