Evidence map›Paper›PMID 36042473›Full record

ArticleBMC nursing2022

Assessment of knowledge, practices, and barriers to pharmacovigilance among nurses at a teaching hospital, Ghana: a cross‑sectional study.

Paa Kofi Tawiah Adu-Gyamfi, Kwesi Boadu Mensah, Joseph Ocansey, Aliu Moomin, Bright Owusu Danso, Frank Agyapong, Reginald Arthur-Mensah Jnr

Open access · goldAbstract read
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Article in BMC nursing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Paa Kofi Tawiah Adu-GyamfiDepartment of Nursing and Midwifery, Faculty of Health and Allied Sciences, Pentecost University Accra, Accra, Ghana. Paakofi62@gmail.com.
Kwesi Boadu MensahDepartment of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Science, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Joseph OcanseyDepartment of Nursing and Midwifery, Faculty of Health and Allied Sciences, Pentecost University Accra, Accra, Ghana.
Aliu MoominSchool of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen, UK.
Bright Owusu DansoDepartment of Nursing and Midwifery, Faculty of Health and Allied Sciences, Pentecost University Accra, Accra, Ghana.
Frank AgyapongDepartment of Nursing and Midwifery, Faculty of Health and Allied Sciences, Pentecost University Accra, Accra, Ghana.
Reginald Arthur-Mensah JnrDepartment of Nursing and Midwifery, Faculty of Health and Allied Sciences, Pentecost University Accra, Accra, Ghana.
Pentecost University College · GHKwame Nkrumah University of Science and Technology · GHRobert Gordon University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPharmacovigilance may be defined as the continuous monitoring of the reaction between a drug agent or combination of drugs a patient took and steps taken to prevent any associated risk. Clinical trials conducted before drug approval cannot uncover every aspect of the health hazards of approved drugs. People with carefully selected characteristics are monitored for the safety and efficacy of the drug; hence, common adverse drug reactions (ADRs) following proper use of the medication can be detected. This calls for continuous monitoring of drugs to report any undocumented ADRs during the clinical trial. The study aimed to assess the knowledge, practice, and barriers to pharmacovigilance among nurses at a teaching hospital.

methodsThe study was a descriptive cross-sectional study, and a stratified sampling technique was used to select 125 nurses within the three units: medical, surgical, and pediatric wards. A structured questionnaire was developed and used for data collection based on the study's objectives and reviewed literature.

resultsThe majority (67.2%) of the respondents were females, and 32.8% were males. Most (71.2%) of the nurses had low knowledge of ADR reporting procedures. Also, 84.8% of the nurses knew the purpose of reporting ADRs. The purpose of ADR reporting, as perceived by respondents, was to identify safe drugs (80.8%) and calculate the incidence of ADR (75.2%). Additionally, among the nurses who reported having nursed a patient with ADRs, 52.54% stated they reported the case, while 47.46% did not report it. The most cited reason for not reporting ADRs was that nurses considered the reaction normal and commonly associated with that medicine (35.7%). In comparison, 28.5% of the nurses said they did not know they were supposed to report the adverse drug reaction. There was no statistically significant difference between ranks of nurses, ward, attending in-service training, and pharmacovigilance practice.

conclusionIn conclusion, nurses in this study had inadequate knowledge of pharmacovigilance and its reporting procedure. The study found that most nurses fear that reporting ADRs may be wrong because most of the nurses in the study did not have any form of pharmacovigilance training.

Indexed as

Adverse drug reactionAdverse drug reaction reporting systemsNursesPharmacovigilance

Identifiers

PMID36042473
PMCPMC9427070
OpenAlexW4293585839

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.