Evidence map›Paper›PMID 36042341›Full record

ArticleScientific reports2022

Activation of recombinational repair in Ewing sarcoma cells carrying EWS-FLI1 fusion gene by chromosome translocation.

Kazuhiro Tanaka, Keiji Suzuki, Kaname Miyashita, Kentaro Wakasa, Masanori Kawano, Yoshimichi Nakatsu, Hiroshi Tsumura, Mitsuaki A Yoshida, Shinya Oda

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Kazuhiro Tanaka *Department of Orthopaedic Surgery, Oita University, Yufu, 879-5593, Japan. ktanaka@oita-u.ac.jp.
Keiji Suzuki *Department of Radiation Medical Sciences, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, 852-8523, Japan.
Kaname MiyashitaClinical Research Institute, Cancer Genetics Laboratory, National Hospital Organization Kyushu Cancer Center, Fukuoka, 811-1395, Japan.
Kentaro WakasaClinical Research Institute, Cancer Genetics Laboratory, National Hospital Organization Kyushu Cancer Center, Fukuoka, 811-1395, Japan.
Masanori KawanoDepartment of Orthopaedic Surgery, Oita University, Yufu, 879-5593, Japan.
Yoshimichi NakatsuDepartment of Medical Biophysics and Radiation Biology, Faculty of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Hiroshi TsumuraDepartment of Orthopaedic Surgery, Oita University, Yufu, 879-5593, Japan.
Mitsuaki A YoshidaClinical Research Institute, Cancer Genetics Laboratory, National Hospital Organization Kyushu Cancer Center, Fukuoka, 811-1395, Japan.
Shinya OdaClinical Research Institute, Cancer Genetics Laboratory, National Hospital Organization Kyushu Cancer Center, Fukuoka, 811-1395, Japan. oda.shinya.zq@mail.hosp.go.jp.
National Hospital Organization Kyushu Cancer Center · JPOita University · JPKyushu University · JPNagasaki University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromosome translocation (TL) is an important mode of genomic changes underlying human tumorigenesis, the detailed mechanisms of which are, however, still not well understood. The two major modalities of DNA double strand break repair, i.e. homologous recombination (HR) and non-homologous end-joining (NHEJ), have been hypothesized. In a typical TL

Indexed as

Neuroectodermal Tumors, Primitive, PeripheralSarcoma, EwingCell Line, TumorGene Expression Regulation, NeoplasticHumansOncogene Proteins, FusionProto-Oncogene Protein c-fli-1RNA-Binding Protein EWSTranslocation, GeneticEWS-FLI fusion proteinOncogene Proteins, FusionProto-Oncogene Protein c-fli-1RNA-Binding Protein EWS

Identifiers

PMID36042341
PMCPMC9427769
OpenAlexW4293585639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.