ArticleScientific reports2022
The healthy equine uterus harbors a distinct core microbiome plus a rich and diverse microbiome that varies with geographical location.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- A Comprehensive Review of the Equine Gut Microbiome in Health and Disease.Veterinary sciences · 2026Review
- Insights from healthy mares reveal that mammalian uteri harbor a diverse virome.Scientific reports · 2026Article
- The Equine Reproductive Microbiota: Composition, Dynamics, Dysbiosis, and Implications for Fertility in Mares and Stallions.Animals : an open access journal from MDPI · 2026Review
- Characterization of the Endometrial Microbiota of Healthy Mares Across the Estrous Cycle.Animals : an open access journal from MDPI · 2026Article
- The Uterine Microbiota in Mares With Endometritis: Impacts of Antibiotic Treatment.Veterinary medicine international · 2026Article
- Effects of Intra-uterine Ceftiofur on the Equine Uterine Microbiome.Veterinary sciences · 2025Article
- Lactobacillus Genus Complex Probiotic-Induced Changes on the Equine Clitoral Microbiome.Veterinary sciences · 2025Article
- Fundamentals of microbiome-based therapies for reproductive tract inflammatory diseases in domestic animals.Animal reproduction · 2025Review
- Endometrial microbiome in mares with and without clinical endometritis.Frontiers in veterinary science · 2025Article
- Article
- Vaginal and Uterine Microbiota of Healthy Maiden Mares during Estrus.Veterinary sciences · 2024Article
- Reproductive Tract Microbiota of Mares.Veterinary sciences · 2024Review
- Isolation of lactic acid bacteria from the reproductive tract of mares as potentially beneficial strains to prevent equine endometritis.Veterinary research communications · 2024Article
- Genome Sequence Comparisons between Small and Large Colony Phenotypes of Equine Clinical Isolates ofAnimals : an open access journal from MDPI · 2024Article
- Metagenomic analysis unravels novel taxonomic differences in the uterine microbiome between healthy mares and mares with endometritis.Veterinary medicine and science · 2024Article
- The dogma of the sterile uterus revisited: does microbial seeding occur during fetal life in humans and animals?Reproduction (Cambridge, England) · 2024Review
- Effect of Sampling Method on Detection of the Equine Uterine Microbiome during Estrus.Veterinary sciences · 2023Article
- Antimicrobial Resistance and Extended-Spectrum Beta-Lactamase Genes inPathogens (Basel, Switzerland) · 2023Article
- Metagenetic Analysis of the Pregnant Microbiome in Horses.Animals : an open access journal from MDPI · 2023Article
- The Role of Biofilms in the Pathogenesis of Animal Bacterial Infections.Microorganisms · 2023Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The goal of this study was to understand the composition and existence of the resident uterine microbiome in healthy mares and to establish the presence of a core microbiome for the healthy equine uterus. We analyzed the microbiomes of 35 healthy mares that are long-time residents of three farms in Oklahoma, Louisiana, and Australia as well as that of 19 mares purchased from scattered owners in the Southern Mid-Western states of the United States. Over 6 million paired-end reads of the V4 region of the 16S rRNA gene were obtained resulting in 19,542 unique Amplicon Sequence Variants (ASVs). ASVs were assigned to 17 known phyla and 213 known genera. Most abundant genera across all animals were Pseudomonas (27%) followed by Lonsdalea (8%), Lactobacillus (7.5%), Escherichia/Shigella (4.5%), and Prevotella (3%). Oklahoma and Louisiana samples were dominated by Pseudomonas (75%). Lonsdalea (28%) was the most abundant genus in the Australian samples but was not found in any other region. Microbial diversity, richness, and evenness of the equine uterine microbiome is largely dependent on the geographical location of the animal. However, we observed a core uterine microbiome consisting of Lactobacillus, Escherichia/Shigella, Streptococcus, Blautia, Staphylococcus, Klebsiella, Acinetobacter, and Peptoanaerobacter.
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