Evidence map›Paper›PMID 36042295›Full record

ArticleProstate cancer and prostatic diseases2023

Composite urinary and sexual outcomes after Rezum: an analysis of predictive factors from an Italian multi-centric study.

Davide Campobasso, Giampaolo Siena, Paolo Chiodini, Enrico Conti, Francesco Franzoso, Daniele Maruzzi, Evangelista Martinelli, Francesco Varvello, Cosimo De Nunzio, Riccardo Autorino and 3 more

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Article in Prostate cancer and prostatic diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Davide Campobasso *Department of Urology, University Hospital of Parma/Azienda Ospedaliero-Universitaria di Parma, Parma, Italy. d.campobasso@virgilio.it.ORCID 0000-0003-2072-114X
Giampaolo Siena *Department of Urology, Careggi Hospital, University of Florence, "San Luca Nuovo", Florence, Italy.
Paolo ChiodiniMedical Statistics Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Enrico ContiDepartment of Urology, Levante Ligure Hospital, La Spezia, Italy.ORCID 0000-0002-5481-9930
Francesco FranzosoDepartment of Urology, Desio Hospital, Desio, Italy.
Daniele MaruzziDepartment of Urology, "S. Maria Degli Angeli" Hospital, Pordenone, Italy.
Evangelista MartinelliDepartment of Urology, "SS. Annunziata" Hospital, Taranto, Italy.ORCID 0000-0003-1436-9354
Francesco VarvelloDepartment of Urology, "Michele e Pietro Ferrero" Hospital, Alba-Bra, Italy.
Cosimo De NunzioDepartment of Urology, "Sant'Andrea" Hospital, Sapienza University, Roma, Italy.ORCID 0000-0002-2190-512X
Riccardo AutorinoDivision of Urology, Virginia Commonwealth University (VCU) Health, Richmond, VA, USA.ORCID 0000-0001-7045-7725
Bhaskar Kumar SomaniDepartment of Urology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Giovanni FerrariDepartment of Urology, "Hesperia Hospital", and CURE Group, Modena, Italy.
Luca CindoloDepartment of Urology, "Hesperia Hospital", and CURE Group, Modena, Italy.ORCID 0000-0002-0712-2719

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Rezum system is one of the latest minimally invasive surgical treatments for benign prostatic hyperplasia.

methodsWe retrospectively reviewed all patients who underwent the Rezum treatment in seven different Italian institutions. A successful urinary outcome was defined as: ≥50% improvement in the IPSS <7, improvement in peak flow ≥50% and/or more than 15 ml/s, ≥1-point improvement in the QoL questionnaire and in the absence of perioperative major complications (AUR, transfusion) or postoperative incontinence. A successful sexual outcome was defined as postoperative (latest follow up consultation) antegrade ejaculation or no variation in ejaculatory function and an increase, or stability or max 1 class reduction, in IIEF-5.

results262 patients were enrolled with a follow-up period of 11 months (IQR 5-15). No early or late serious adverse events (Clavien III-IV) occurred. Early complications occurred in 39.3% of cases, with 4 cases of clot retention and one case of blood transfusion. Urge incontinence was reported by 6 patients (2.2%). A treatment failure requiring re-intervention occurred in 4 cases (1.5%). The preoperative antegrade ejaculation rate was 56.5%, and after the procedure it increased to 78.2%. The increase of ≥1-point in the QoL was achieved in 92.7% of the cases. Optimal urinary and sexual outcomes were achieved in 52.9% and 87.8%, respectively.

conclusionsIn our series, water vapor intraprostatic injections seem to be an effective and safe procedure.

Indexed as

Lower Urinary Tract SymptomsProstatic HyperplasiaProstatic NeoplasmsHumansMaleQuality of LifeRetrospective StudiesTreatment Outcome

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.