Evidence map›Paper›PMID 36042243›Full record

ArticleScientific reports2022

Silver nanoparticles synthesized from the seaweed Sargassum polycystum and screening for their biological potential.

Rajasekar Thiurunavukkarau, Sabarika Shanmugam, Kumaran Subramanian, Priyadarshini Pandi, Gangatharan Muralitharan, Maryshamya Arokiarajan, Karthika Kasinathan, Anbarasu Sivaraj, Revathy Kalyanasundaram, Suliman Yousef AlOmar and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 56 citations in OpenAlex.

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  13. Phyto-synthesized silver nanoparticles fromFrontiers in plant science · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Rajasekar Thiurunavukkarau *Centre for Drug Discovery and Development, Col. Dr. Jeppiaar Research Park, Sathyabama Institute of Science and Technology Jeppiaar Nagar, Rajiv Gandhi Road, Chennai, 600 119, India. microraja09@gmail.com.
Sabarika Shanmugam *Departmentof Microbiology, Centre of Excellence in Life Sciences, Bharathidasan University, Tiruchirappalli, 620 024, Tami Nadu, India.
Kumaran SubramanianCentre for Drug Discovery and Development, Col. Dr. Jeppiaar Research Park, Sathyabama Institute of Science and Technology Jeppiaar Nagar, Rajiv Gandhi Road, Chennai, 600 119, India. kumarun23@gmail.com.
Priyadarshini PandiDepartment of Biotechnology, Mohamed Sathak College of Arts and Science, Chennai, Tamil Nadu, India.
Gangatharan MuralitharanDepartmentof Microbiology, Centre of Excellence in Life Sciences, Bharathidasan University, Tiruchirappalli, 620 024, Tami Nadu, India.
Maryshamya ArokiarajanCentre for Drug Discovery and Development, Col. Dr. Jeppiaar Research Park, Sathyabama Institute of Science and Technology Jeppiaar Nagar, Rajiv Gandhi Road, Chennai, 600 119, India.
Karthika KasinathanDepartmentof Microbiology, Centre of Excellence in Life Sciences, Bharathidasan University, Tiruchirappalli, 620 024, Tami Nadu, India.
Anbarasu SivarajCentre for Drug Discovery and Development, Col. Dr. Jeppiaar Research Park, Sathyabama Institute of Science and Technology Jeppiaar Nagar, Rajiv Gandhi Road, Chennai, 600 119, India.
Revathy KalyanasundaramCentre for Drug Discovery and Development, Col. Dr. Jeppiaar Research Park, Sathyabama Institute of Science and Technology Jeppiaar Nagar, Rajiv Gandhi Road, Chennai, 600 119, India.
Suliman Yousef AlOmarDepartment of Zoology, College of Science, Kind Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.
Velmurugan ShanmugamMadda Walabu University, Robe, Ethiopia. velkas.cas@gmail.com.
Sathyabama Institute of Science and Technology · INBharathidasan University · INKing Saud University · SAMadda Walabu University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

World-wide antimicrobial resistant is biggest threat in global health. It requires the urgent need of multisectoral action for the scientific community to achieve the sustainable development Goals. Due to their antimicrobial properties, silver nanoparticles are potential activates to pathogens, which explains their potential for multiple applications in various fields. In the present studies, we evaluate the antimicrobial properties of a Sargassum polycystum algal extract, an unrivaled green synthetic method for producing -defined shaped seaweed silver nanoparticles. To confirm their structure and size, some characterization techniques are used, such as Absorption spectrophotometer (UV-VIS), Fourier transforms infrared spectroscopy (FTIR), Scanning electron Microscope (SEM), Transmission electron microscopy (TEM) and X-Ray diffraction (XRD). Evaluate the antibacterial and anti-mycobacterial activity using silver nanoparticles. The toxicity study of this silver nanoparticle has been done with the help of zebrafish larva. The biological nanoparticle having good antimicrobial activity against Staphylococcus aureus, Micrococcus luteus, Pseudomonas fluorescens and Candida albicans and also it shows potent activity against MTB H37Rv, SHRE sensitive MTB Rifampicin resistant MTB around 98%. Seaweed nanoparticles had lower toxicity for the survival of the fish larvae. In comparison, other dosages will arrest the cell cycle and leads to death. The present finding revealed that these seaweeds nanoparticles have potential anti-mycobacterial activity against pathogens at low concentrations. This makes them a potent source of antibacterial and anti-TB agents.

Indexed as

Anti-Infective AgentsMetal NanoparticlesSargassumSeaweedAnimalsAnti-Bacterial AgentsLarvaPlant ExtractsSilverSpectroscopy, Fourier Transform InfraredX-Ray DiffractionZebrafishAnti-Bacterial AgentsAnti-Infective AgentsPlant ExtractsSilver

Identifiers

PMID36042243
PMCPMC9427740
OpenAlexW4293574965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.